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oai:repisalud.isciii.es:20.500.12105/225872024-11-28T20:58:55Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967

00925njm 22002777a 4500 dc Ferrer, Miguel D author Capó Fiol, Xavier author Martorell, Miquel author Busquets-Cortés, Carla author Bouzas, Cristina author Carreres, Sandra author Mateos, David author Soldevila Verdeguer, Carla author Tur, Josep A author Pons, Antoni author 2018-11 A chronic inflammatory state is a major characteristic of the aging process, and physical activity is proposed as a key component for healthy aging. Our aim was to evaluate the body composition, hypertension, lipid profile, and inflammatory status of older adults, and these factors' association with physical activity. A total of 116 elderly volunteers were categorized into terciles of quantitative metabolic equivalents of task (MET). Subjects in the first and third terciles were defined as sedentary and active subjects, respectively. Anthropometric and biochemical parameters, hemograms, and inflammatory markers were measured in plasma or peripheral mononuclear blood cells (PBMCs). The active groups exercised more than their sedentary counterparts. The practice of physical activity was accompanied by lower weight, fat mass, body mass index, and diastolic blood pressure when compared to a more sedentary life-style. Physical activity also lowered the haematocrit and total leukocyte, neutrophil, and lymphocyte counts. The practice of exercise induced a decrease in the IL-6 circulating levels and the TLR2 protein levels in PBMCs, while the expression of the anti-inflammatory IL-10 was activated in active subjects. The regular practice of physical activity exerts beneficial effects on body composition and the anti-inflammatory status of old people. Ferrer MD, Capo Fiol X, Martorell M, Busquets-Cortes C, Bouzas Velasco C, Carreres Rey S, et al. Regular Practice of Moderate Physical Activity by Older Adults Ameliorates Their Anti-Inflammatory Status. Nutrients. 2018 Nov;10(11):1780. 10.3390/nu10111780 2072-6643 Nutrients http://hdl.handle.net/20.500.13003/9046 30453505 L625047759 2-s2.0-85056723724 https://hdl.handle.net/20.500.12105/22587 451547700218 Immunity Inflammation Metabolism Physical activity Regular Practice of Moderate Physical Activity by Older Adults Ameliorates Their Anti-Inflammatory Status