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Repisalud author Santos, Susana author Eekhout, Iris author Voerman, Ellis author Gaillard, Romy author Barros, Henrique author Charles, Marie-Aline author Chatzi, Leda author Chevrier, Cecile author Chrousos, George P author Corpeleijn, Eva author Costet, Nathalie author Crozier, Sarah author Doyon, Myriam author Eggesbo, Merete author Fantini, Maria Pia author Farchi, Sara author Forastiere, Francesco author Gagliardi, Luigi author Georgiu, Vagelis author Godfrey, Keith M author Gori, Davide author Grote, Veit author Hanke, Wojciech author Hertz-Picciotto, Irva author Heude, Barbara author Hivert, Marie-France author Hryhorczuk, Daniel author Huang, Rae-Chi author Inskip, Hazel author Jusko, Todd A author Karvonen, Anne M author Koletzko, Berthold author Kupers, Leanne K author Lagstrom, Hanna author Lawlor, Debbie A author Lehmann, Irina author Lopez-Espinosa, Maria-Jose author Magnus, Per author Majewska, Renata author Makela, Johanna author Manios, Yannis author McDonald, Sheila W author Mommers, Monique author Morgen, Camilla S author Moschonis, George author Murinova, Lubica author Newnham, John author Nohr, Ellen A author Andersen, Anne-Marie Nybo author Oken, Emily author Oostvogels, Adriette J. J. M author Pac, Agnieszka author Papadopoulou, Eleni author Pekkanen, Juha author Pizzi, Costanza author Polanska, Kinga author Porta, Daniela author Richiardi, Lorenzo author Rifas-Shiman, Sheryl L author Roeleveld, Nel author Santa-Marina, Loreto author Santos, Ana C author Smit, Henriette A author Sorensen, Thorkild I. A author Standl, Marie author Stanislawski, Maggie author Stoltenberg, Camilla author Thiering, Elisabeth author Thijs, Carel author Torrent Quetglas, Maties author Tough, Suzanne C author Trnovec, Tomas author van Gelder, Marleen M. H. J author van Rossem, Lenie author von Berg, Andrea author Vrijheid, Martine author Vrijkotte, Tanja G. M author Zvinchuk, Oleksandr author van Buuren, Stef author Jaddoe, Vincent W. V. 2024-09-06T09:53:52Z 2024-09-06T09:53:52Z 2018-11-05 Santos S, Eekhout I, Voerman E, Gaillard R, Barros H, Charles MA, et al. Gestational weight gain charts for different body mass index groups for women in Europe, North America, and Oceania. BMC Med. 2018 Nov 05;16:201. 10.1186/s12916-018-1189-1 1741-7015 BMC Medicine http://hdl.handle.net/20.500.13003/9026 30396358 L624752833 2-s2.0-85056143604 https://hdl.handle.net/20.500.12105/22551 449266800001 Background: Gestational weight gain differs according to pre-pregnancy body mass index and is related to the risks of adverse maternal and child health outcomes. Gestational weight gain charts for women in different pre-pregnancy body mass index groups enable identification of women and offspring at risk for adverse health outcomes. We aimed to construct gestational weight gain reference charts for underweight, normal weight, overweight, and grades 1, 2 and 3 obese women and to compare these charts with those obtained in women with uncomplicated term pregnancies. Methods: We used individual participant data from 218,216 pregnant women participating in 33 cohorts from Europe, North America, and Oceania. Of these women, 9065 (4.2%), 148,697 (68.1%), 42,678 (19.6%), 13,084 (6.0%), 3597 (1.6%), and 1095 (0.5%) were underweight, normal weight, overweight, and grades 1, 2, and 3 obese women, respectively. A total of 138, 517 women from 26 cohorts had pregnancies with no hypertensive or diabetic disorders and with term deliveries of appropriate for gestational age at birth infants. Gestational weight gain charts for underweight, normal weight, overweight, and grade 1, 2, and 3 obese women were derived by the Box-Cox t method using the generalized additive model for location, scale, and shape. Results: We observed that gestational weight gain strongly differed per maternal pre-pregnancy body mass index group. The median (interquartile range) gestational weight gain at 40 weeks was 14.2kg (11.4-17.4) for underweight women, 14.5kg (11.5-17.7) for normal weight women, 13.9kg (10.1-17.9) for overweight women, and 11.2kg (7.0-15.7), 8.7kg (4.3-13.4) and 6.3kg (1.9-11.1) for grades 1, 2, and 3 obese women, respectively. The rate of weight gain was lower in the first half than in the second half of pregnancy. No differences in the patterns of weight gain were observed between cohorts or countries. Similar weight gain patterns were observed in mothers without pregnancy complications. Conclusions: Gestational weight gain patterns are strongly related to pre-pregnancy body mass index. The derived charts can be used to assess gestational weight gain in etiological research and as a monitoring tool for weight gain during pregnancy in clinical practice. eng Weight gain Pregnancy Charts References Gestational weight gain charts for different body mass index groups for women in Europe, North America, and Oceania research article