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oai:repisalud.isciii.es:20.500.12105/204862024-11-29T01:34:22Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967

00925njm 22002777a 4500 dc Creus-Cuadros, Anna author Tresserra-Rimbau, Anna author Quifer-Rada, Paola author Angel Martinez-Gonzalez, Miguel author Corella, Dolores author Salas-Salvao, Jordi author Fito, Montserrat author Estruch, Ramon author Gomez-Gracia, Enrique author Lapetra, Jose author Aros, Fernando author Ros, Emili author Serra-Majem, Lluis author Pinto, Xavier author Jose Moreno, Juan author Ruiz-Canela, Miguel author Vicente Sorli, Jose author Basora, Josep author Schroeder, Helmut author Maria Lamuela-Raventos, Rosa author PREDIMED Study Investigators author 2017-04 Background The study of dietary patterns is gaining interest. Although the health benefits of yogurt and lignans have been investigated separately, to our knowledge there are no studies on their associative effects. Objective The aim of this study was to evaluate a possible association between yogurt and lignans using biomarkers of cardiovascular disease risk in an elderly population. Design We conducted a cross-sectional analysis of the association between baseline dietary information and cardiovascular risk parameters using food frequency questionnaires. Participants We enrolled 7,169 Spanish participants of the PREDIMED (Prevencion con Dieta Mediterranea) study (elderly men and women at high cardiovascular risk) from June 2003 to June 2009. Main outcome measures Cardiovascular risk parameters, including cholesterol, tri-glycerides, glucose, body mass index, weight, waist circumference, and blood pressure were measured. Statistical analysis General linear models were used to assess the relationship between categorical variables (yogurt, total dairy intake, lignans, and yogurt plus lignans) and cardiovascular risk parameters. Results The consumption of either yogurt or lignans seems to have beneficial effects on human health, but the consumption of both showed greater improvement in some cardiovascular health parameters. Indeed, participants with a higher consumption of both yogurt and lignans showed lower total cholesterol (estimated beta-coefficients= -6.18; P=0.001) and low-density lipoprotein cholesterol levels (beta=-4.92; P=0.005). In contrast, participants with lower yogurt and lignan consumption had a higher body mass index (beta=0.28; P=0.007) and weight (beta=1.20; P=0.008). Conclusions High lignan and yogurt consumption is associated with a better cardiovascular risk parameters profile in an elderly Mediterranean population. Further research is warranted to determine the mechanisms and consequences of this potential effect. Creus-Cuadros Anna, Tresserra-Rimbau Anna, Quifer-Rada Paola, Angel Martinez-Gonzalez Miguel, Corella Dolores, Salas-Salvao Jordi, et al. Associations between Both Lignan and Yogurt Consumption and Cardiovascular Risk Parameters in an Elderly Population: Observations from a Cross-Sectional Approach in the PREDIMED Study. J Acad Nutr Diet. 2017 Apr;117(4):609-622. Epub 2016 Dec 29. 10.1016/j.jand.2016.11.003 2212-2680 2212-2672 Journal of the Academy of Nutrition and Dietetics http://hdl.handle.net/20.500.13003/9896 28041856 L617092232 2-s2.0-85009373495 http://hdl.handle.net/20.500.12105/20486 398758200014 Polyphenol Lipid profile Cardiovascular disease Microbiota Associations between Both Lignan and Yogurt Consumption and Cardiovascular Risk Parameters in an Elderly Population: Observations from a Cross-Sectional Approach in the PREDIMED Study