2026-07-23T17:12:32Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/204842025-04-23T07:55:50Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967
00925njm 22002777a 4500
dc
Tyrovolas, Stefanos
author
Polychronopoulos, Evangelos
author
Mariolis, Anargiros
author
Piscopo, Suzanne
author
Valacchi, Giuseppe
author
Makri, Kornilia
author
Zeimbekis, Akis
author
Tyrovola, Dimitra
author
Bountziouka, Vassiliki
author
Gotsis, Efthimios
author
Metallinos, George
author
Tur, Josep A
author
Matalas, Antonia
author
Lionis, Christos
author
Haro, Josep Maria
author
Panagiotakos, Demosthenes B
author
2017-02
The aim of the present study was to evaluate the role of parental longevity and parental cardiovascular disease (CVD) history in CVD risk and successful aging of a random sample of older adults living in the Mediterranean basin and who participated in the MEDiterranean Islands (MEDIS) study. During 2005 to 2011, 2663 elders were voluntarily enrolled. A multidimensional successful aging index consisting of 10 components was used. Paternal and maternal longevity was defined as those older participants of whom both parents lived above the age of 90. The burden of CVD-related factors (CVD-RFs) was calculated as the total score of 4 major CVD-RFs (range 0-4). After adjustment, parental longevity was inversely associated with the burden of CVD-RFs (P = .04). Moreover, parental longevity was positively associated with the older adults' successful aging score (-coefficient [95% confidence interval]: .38 [0.06-0.71]). Parent's long living was revealed as an important factor for successful aging and for reduced CVD risk, suggesting that further research is needed in the genetic predisposition of longevity.
Tyrovolas Stefanos, Polychronopoulos Evangelos, Mariolis Anargiros, Piscopo Suzanne, Valacchi Giuseppe, Makri Kornilia, et al. Is Parental Longevity Associated With the Cardiovascular Risk and the Successful Aging of Their Offspring? Results From the Multinational MEDIS Study. Angiology. 2017 Feb;68(2):124-131. Epub 2016 Jul 11.
10.1177/0003319716642140
1940-1574
0003-3197
Angiology
http://hdl.handle.net/20.500.13003/9965
27069110
L613905321
2-s2.0-85007343613
http://hdl.handle.net/20.500.12105/20484
391460300006
Parental longevity
Successful aging
Cardiovascular disease
Older adults
Mediterranean basin
Is Parental Longevity Associated With the Cardiovascular Risk and the Successful Aging of Their Offspring? Results From the Multinational MEDIS Study