2026-08-29T19:28:20Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/204732024-11-28T20:39:54Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967

00925njm 22002777a 4500 dc Sabater, Sebastia author Andres, Ignacio author Lopez-Honrubia, Veronica author Berenguer, Roberto author Sevillano, Marimar author Jiménez-Jiménez, Esther author Rovirosa, Angeles author Arenas, Meritxell author 2017 Endometrial cancer (EC) is one of the most common gynecological cancers among women in the developed countries. Vaginal cuff is the main location of relapses after a curative surgical procedure and postoperative radiation therapy have proven to diminish it. Nevertheless, these results have not translated into better survival results. The preeminent place of vaginal cuff brachytherapy (VCB) in the postoperative treatment of high-to intermediate-risk EC was given by the PORTEC-2 trial, which demonstrated a similar reduction in relapses with VCB than with external beam radiotherapy (EBRT), but VCB induced less late toxicity. As a result of this trial, the use of VCB has increased in clinical practice at the expense of EBRT. A majority of the clinical reviews of VCB usually address the risk categories and patient selection but pay little attention to technical aspects of the VCB procedure. Our review aimed to address both aspects. First of all, we described the risk groups, which guide patient selection for VCB in clinical practice. Then, we depicted several technical aspects that might influence dose deposition and toxicity. Bladder distension and rectal distension as well as applicator position or patient position are some of those variables that we reviewed. Sabater S, Andres I, Lopez-Honrubia V, Berenguer R, Sevillano M, Jimenez-Jimenez E, et al. Vaginal cuff brachytherapy in endometrial cancer - a technically easy treatment?. Cancer Manag Res. 2017;9:351-62. 10.2147/CMAR.S119125 1179-1322 Cancer Management and Research http://hdl.handle.net/20.500.13003/17174 28848362 L618493505 2-s2.0-85030254623 http://hdl.handle.net/20.500.12105/20473 407381100001 Endometrial cancer Vaginal cuff brachytherapy Rectum Bladder Technique Vaginal cuff brachytherapy in endometrial cancer - a technically easy treatment?