2026-06-14T03:33:13Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/204412024-11-28T19:36:54Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967
Repisalud
author
Rodriguez, Alejandro
author
Tembl, Jose
author
Mesa-Gresa, Patricia
author
Angel Munoz, Miguel
author
Montoya, Pedro
author
Rey, Beatriz
2024-07-11T09:10:36Z
2024-07-11T09:10:36Z
2017-07-12
Rodriguez A, Tembl J, Mesa-Gresa P, Muñoz MA, Montoya P, Rey B. Altered cerebral blood flow velocity features in fibromyalgia patients in resting-state conditions. PLoS One. 2017 Jul 12;12(7):e0180253.
10.1371/journal.pone.0180253
1932-6203
PloS One
http://hdl.handle.net/20.500.13003/9746
28700720
L617275921
2-s2.0-85023174989
http://hdl.handle.net/20.500.12105/20441
405649600024
The aim of this study is to characterize in resting-state conditions the cerebral blood flow velocity (CBFV) signals of fibromyalgia patients. The anterior and middle cerebral arteries of both hemispheres from 15 women with fibromyalgia and 15 healthy women were monitored using Transcranial Doppler (TCD) during a 5-minute eyes-closed resting period. Several signal processing methods based on time, information theory, frequency and time-frequency analyses were used in order to extract different features to characterize the CBFV signals in the different vessels. Main results indicated that, in comparison with control subjects, fibromyalgia patients showed a higher complexity of the envelope CBFV and a different distribution of the power spectral density. In addition, it has been observed that complexity and spectral features show correlations with clinical pain parameters and emotional factors. The characterization features were used in a lineal model to discriminate between fibromyalgia patients and healthy controls, providing a high accuracy. These findings indicate that CBFV signals, specifically their complexity and spectral characteristics, contain information that may be relevant for the assessment of fibromyalgia patients in resting-state conditions.
eng
Altered cerebral blood flow velocity features in fibromyalgia patients in resting-state conditions
research article