2026-06-14T05:08:08Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/204412024-11-28T19:36:54Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967

00925njm 22002777a 4500 dc Rodriguez, Alejandro author Tembl, Jose author Mesa-Gresa, Patricia author Angel Munoz, Miguel author Montoya, Pedro author Rey, Beatriz author 2017-07-12 The aim of this study is to characterize in resting-state conditions the cerebral blood flow velocity (CBFV) signals of fibromyalgia patients. The anterior and middle cerebral arteries of both hemispheres from 15 women with fibromyalgia and 15 healthy women were monitored using Transcranial Doppler (TCD) during a 5-minute eyes-closed resting period. Several signal processing methods based on time, information theory, frequency and time-frequency analyses were used in order to extract different features to characterize the CBFV signals in the different vessels. Main results indicated that, in comparison with control subjects, fibromyalgia patients showed a higher complexity of the envelope CBFV and a different distribution of the power spectral density. In addition, it has been observed that complexity and spectral features show correlations with clinical pain parameters and emotional factors. The characterization features were used in a lineal model to discriminate between fibromyalgia patients and healthy controls, providing a high accuracy. These findings indicate that CBFV signals, specifically their complexity and spectral characteristics, contain information that may be relevant for the assessment of fibromyalgia patients in resting-state conditions. Rodriguez A, Tembl J, Mesa-Gresa P, Muñoz MA, Montoya P, Rey B. Altered cerebral blood flow velocity features in fibromyalgia patients in resting-state conditions. PLoS One. 2017 Jul 12;12(7):e0180253. 10.1371/journal.pone.0180253 1932-6203 PloS One http://hdl.handle.net/20.500.13003/9746 28700720 L617275921 2-s2.0-85023174989 http://hdl.handle.net/20.500.12105/20441 405649600024 Altered cerebral blood flow velocity features in fibromyalgia patients in resting-state conditions