2026-04-29T12:24:11Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/204272024-11-29T02:38:33Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967
Repisalud
author
Farooqi, Ammad Ahmad
author
Fayyaz, Sundas
author
Sanches Silva, Ana
author
Soldevila Verdeguer, Carla
author
Nabavi, Seyed Fazel
author
Mocan, Andrei
author
Nabavi, Seyed Mohammad
author
Bishayee, Anupam
2024-07-11T09:10:31Z
2024-07-11T09:10:31Z
2017-05
Farooqi Ammad A, Fayyaz S, Sanches Silva A, Sureda Gomila A, Nabavi Seyed F, Mocan A, et al. Oleuropein and Cancer Chemoprevention: The Link is Hot. Molecules. 2017 May;22(5):705.
10.3390/molecules22050705
1420-3049
Molecules
http://hdl.handle.net/20.500.13003/9839
28468276
L617825666
2-s2.0-85020222655
http://hdl.handle.net/20.500.12105/20427
404522900028
Cancer comprises a collection of related diseases characterized by the existence of altered cellular pathways resulting in an abnormal tendency for uncontrolled growth. A broad spectrum, coordinated, and personalized approach focused on targeting diverse oncogenic pathways with low toxicity and economic natural compounds can provide a real benefit as a chemopreventive and/or treatment of this complex disease. Oleuropein, a bioactive phenolic compound mainly present in olive oil and other natural sources, has been reported to modulate several oncogenic signalling pathways. This review presents and critically discusses the available literature about the anticancer and onco-suppressive activity of oleuropein and the underlying molecular mechanisms implicated in the anticarcinogenic and therapeutic effects. The existence of limitations and the promising perspectives of research on this phenolic compound are also critically analyzed and discussed.
eng
Cancer
Chemopreventive effect
Oleuropein
Olive oil
Oleuropein and Cancer Chemoprevention: The Link is Hot
review article