2026-05-22T05:27:55Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/203132024-11-29T02:52:54Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967
Repisalud
author
Tyrovolas, Stefanos
author
Haro, Josep Maria
author
Mariolis, Anargiros
author
Piscopo, Suzanne
author
Valacchi, Giuseppe
author
Bountziouka, Vassiliki
author
Anastasiou, Foteini
author
Zeimbekis, Akis
author
Tyrovola, Dimitra
author
Foscolou, Alexandra
author
Gotsis, Efthimios
author
Metallinos, George
author
Tur, Josep A
author
Matalas, Antonia
author
Lionis, Christos
author
Polychronopoulos, Evangelos
author
Panagiotakos, Demosthenes
2024-07-09T09:14:37Z
2024-07-09T09:14:37Z
2016-09
Tyrovolas Stefanos, Haro Josep-Maria, Mariolis Anargiros, Piscopo Suzanne, Valacchi Giuseppe, Bountziouka Vassiliki, et al. Skeletal muscle mass and body fat in relation to successful ageing of older adults: The multi-national MEDIS study. Arch Gerontol Geriatr. 2016 Sep;66:95-101. Epub 2016 May 9.
10.1016/j.archger.2016.04.017
1872-6976
0167-4943
Archives of Gerontology and Geriatrics
http://hdl.handle.net/20.500.13003/10216
27266673
L610588866
2-s2.0-84971633033
http://hdl.handle.net/20.500.12105/20313
381646000014
Background: The determinants that promote successful ageing still remain unknown. The aim of the present work was to evaluate the role of skeletal muscle mass and body fat percentage (BF%), in the level of successful ageing. Methods: during 2005-2011, 2663 older (aged 65-100 years) from 21 Mediterranean islands and the rural Mani region (Peloponnesus) of Greece were voluntarily enrolled in the study. Appendicular skeletal muscle mass (ASM), skeletal muscle mass index (SMI) and BF% were calculated using population formulas. Dietary habits, energy intake, expenditure and energy balance were derived throughout standard procedures. A successful ageing index ranging from 0 to 10 was used. Results: The mean ASM mass was 24 +/- 6.0 kg, the SMI was 0.84 +/- 0.21 and the BF% was 44%. Females had lower SMI and higher BF% in comparison with males, respectively [(SMI: 0.66 +/- 0.09 vs. 1.03 +/- 0.11; BF%: 51% vs. 34%, (p < 0.001)]. High successful agers had better rates in ASM (p = 0.01), SMI (p < 0.001) and BF% (p < 0.001), compared with the medium and low successful ones. Changes in SMI [b-coefficient (95% CI): 2.14 (1.57 to 2.71)] were positively associated with successful ageing, while changes in BF% [b-coefficient (95% CI): -0.04 (-0.05 to -0.03)] were inversely associated with successful ageing. Results from sensitivity analysis showed that the effects of variations on body composition were consistent, less pronounced in the positive energy balance group and more pronounced among the oldest old. Conclusions: Body composition changes seem to be associated with lower quality of life in the older adults, as measured through successful ageing.
eng
Successful ageing
Appendicular skeletal muscle mass
Body fat
Energy balance
Older adults
Skeletal muscle mass and body fat in relation to successful ageing of older adults: The multi-national MEDIS study
research article