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00925njm 22002777a 4500 dc Verd, Sergio author De Sotto Esteban, Diego author Fernandez, Consuelo author Gutierrez, Antonio author 2016-11 Gestational diabetes increases the risk of a range of adverse perinatal outcomes, including breastfeeding failure, but the best cut-off point for gestational diabetes is unknown. The purpose of this study was to evaluate the association between mild gestational glucose tolerance impairment and the early cessation of exclusive breastfeeding (EBF). This is an observational study of 768 women with full term pregnancies that were screened for gestational diabetes at 24-28 weeks gestation. Subjects were divided into two groups: those with a normal 1-h glucose challenge test and those with an elevated 1-h glucose challenge test but still did not qualify for gestational diabetes. We constructed multivariable logistic regression models using data from 616 women with normal gestational glucose tolerance and 152 women with an isolated positive 1-h glucose challenge test. The risk of early exclusive breastfeeding cessation was found to increase in women with mildly impaired glucose tolerance during pregnancy (adjusted OR, 1.65; 95% CI: 1.11, 2.45). Risks of early EBF cessation were also independently associated with the amount of neonatal weight loss and admission to the neonatal ward. Instead, parity was associated with a decreased risk for shorter EBF duration. Insulin resistance-even in the absence of gestational diabetes mellitus-may be an impeding factor for EBF. Verd S, De Sotto D, Fernandez C, Gutierrez A. The Effects of Mild Gestational Hyperglycemia on Exclusive Breastfeeding Cessation. Nutrients. 2016 Nov;8(11):742. 10.3390/nu8110742 2072-6643 Nutrients http://hdl.handle.net/20.500.13003/10095 27869777 L613336365 2-s2.0-84996490784 http://hdl.handle.net/20.500.12105/20294 388666400073 Breastfeeding Gestational diabetes Neonate Glucose tolerance test Prediabetes Insulin resistance Pregnancy outcomes The Effects of Mild Gestational Hyperglycemia on Exclusive Breastfeeding Cessation