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00925njm 22002777a 4500 dc Haaskjold, Yngvar Lunde author Bolkan, Håkon Angell author Krogh, Kurt Østhuus author Jongopi, James author Lundeby, Karen Marie author Mellesmo, Sindre author Garces, Pedro San Jose author Jøsendal, Ola author Øpstad, Åsmund author Svensen, Erling author Zabala Fuentes, Luis Matias author Kamara, Alfred Sandy author Riera, Melchor author Arranz Izquierdo, Javier author Roberts, David P author Stamper, Paul D author Austin, Paula author Moosa, Alfredo J author Marke, Dennis author Hassan, Shoaib author Eide, Geir Egil author Berg, Ase author Blomberg, Bjørn author 2016-09 The 2013-2016 outbreak of Ebola virus disease (EVD) in West Africa infected >28,000 people, including >11,000 who died, and disrupted social life in the region. We retrospectively studied clinical signs and symptoms and risk factors for fatal outcome among 31 Ebola virus positive patients admitted to the Ebola Treatment Center in Moyamba District, Sierra Leone. We found a higher rate of bleeding manifestations than reported elsewhere during the outbreak. Significant predictors for death were shorter time from symptom onset to admission, male sex, high viral load on initial laboratory testing, severe pain, diarrhea, bloody feces, and development of other bleeding manifestations during hospitalization. These risk factors for death could be used to identify patients in need of more intensive medical support. The lack of fever in as many as one third of EVD cases may have implications for temperature-screening practices and case definitions. Lunde Haaskjold Y, Bolkan HA, Osthuus Krogh K, Jongopi J, Lundeby KM, Mellesmo S, et al. Clinical Features of and Risk Factors for Fatal Ebola Virus Disease, Moyamba District, Sierra Leone, December 2014 February 2015. Emerg Infect Dis. 2016 Sep;22(9):1537-44. Epub 2016 Sep 15. 10.3201/eid2209.151621 1080-6059 1080-6040 Emerging Infectious Diseases http://hdl.handle.net/20.500.13003/10215 27268303 L612290680 2-s2.0-84988432066 http://hdl.handle.net/20.500.12105/20284 381955900002 Clinical Features of and Risk Factors for Fatal Ebola Virus Disease, Moyamba District, Sierra Leone, December 2014 February 2015