2026-04-29T16:56:10Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/202392024-11-28T15:54:29Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16938col_20.500.12105_16967col_20.500.12105_16972
Repisalud
author
Plaza, Vicente
author
Fernández-Rodríguez, Concepción
author
Melero, Carlos
author
García-Cosío, Borja
author
Manuel Entrenas, Luis
author
Perez de Llano, Luis Alejandro
author
Gutierrez-Pereyra, Fernando
author
Tarragona, Eduard
author
Palomino, Rosa
author
Lopez-Vina, Antolin
author
TAI Study Grp
2024-07-09T09:13:02Z
2024-07-09T09:13:02Z
2016-04-01
Plaza V, Fernandez-Rodriguez C, Melero C, Cosio BG, Entrenas LM, Perez De Llano L, et al. Validation of the 'Test of the Adherence to Inhalers' (TAI) for Asthma and COPD Patients. J Aerosol Med Pulm Drug Deliv. 2016 Apr 01;29(2):142-52. Epub 2015 Jul 31.
10.1089/jamp.2015.1212
1941-2703
1941-2711
Journal of Aerosol Medicine and Pulmonary Drug Delivery
http://hdl.handle.net/20.500.13003/17304
26230150
L610199098
2-s2.0-84964762520
http://hdl.handle.net/20.500.12105/20239
373922800005
Background: To validate the Test of Adherence to Inhalers' (TAI), a 12-item questionnaire designed to assess the adherence to inhalers in patients with COPD or asthma. Methods: A total of 1009 patients with asthma or COPD participated in a cross-sectional multicenter study. Patients with electronic adherence 80% were defined as adherents. Construct validity, internal validity, and criterion validity were evaluated. Self-reported adherence was compared with the Morisky-Green questionnaire. Results: Factor analysis study demonstrated two factors, factor 1 was coincident with TAI patient domain (items 1 to 10) and factor 2 with TAI health-care professional domain (items 11 and 12). The Cronbach's alpha was 0.860 and the test-retest reliability 0.883. TAI scores correlated with electronic adherence (=0.293, p=0.01). According to the best cut-off for 10 items (score 50, area under the ROC curve 0.7), 569 (62.5%) patients were classified as non-adherents. The non-adherence behavior pattern was: erratic 527 (57.9%), deliberate 375 (41.2%), and unwitting 242 (26.6%) patients. As compared to Morisky-Green test, TAI showed better psychometric properties. Conclusions: The TAI is a reliable and homogeneous questionnaire to identify easily non-adherence and to classify from a clinical perspective the barriers related to the use of inhalers in asthma and COPD.
eng
Anti-asthmatic agents
Administration and dosage
Inhalers
Medication adherence
Medication non-adherence
Questionnaires
Pulmonary disease
Chronic obstructive
Drug therapy
Validation studies
Validation of the 'Test of the Adherence to Inhalers' (TAI) for Asthma and COPD Patients
research article