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00925njm 22002777a 4500 dc Hutchinson, Peter J author Jalloh, Ibrahim author Helmy, Adel author Carpenter, Keri LH author Rostami, Elham author Bellander, Bo-Michael author Boutelle, Martyn G author Chen, Jeff W author Claassen, Jan author Dahyot-Fizelier, Claire author Enblad, Per author Gallagher, Clare N author Helbok, Raimund author Hillered, Lars author Le Roux, Peter D author Magnoni, Sandra author Mangat, Halinder S author Menon, David K author Nordstroem, Carl-Henrik author O'Phelan, Kristine H author Oddo, Mauro author Pérez-Bárcena, Jon author Robertson, Claudia author Ronne-Engstroem, Elisabeth author Sahuquillo, Juan author Smith, Martin author Stocchetti, Nino author Belli, Antonio author Carpenter, T. Adrian author Coles, Jonathan P author Czosnyka, Marek author Dizdar, Nil author Goodman, J. Clay author Gupta, Arun K author Nielsen, Troels H author Marklund, Niklas author Montcriol, Ambroise author O'Connell, Mark T author Poca, Maria A author Sarrafzadeh, Asita author Shannon, Richard J author Skjoth-Rasmussen, Jane author Smielewski, Peter author Stover, John F author Timofeev, Ivan author Vespa, Paul author Zavala, Elizabeth author Ungerstedt, Urban author 2015-09 Microdialysis enables the chemistry of the extracellular interstitial space to be monitored. Use of this technique in patients with acute brain injury has increased our understanding of the pathophysiology of several acute neurological disorders. In 2004, a consensus document on the clinical application of cerebral microdialysis was published. Since then, there have been significant advances in the clinical use of microdialysis in neurocritical care. The objective of this review is to report on the International Microdialysis Forum held in Cambridge, UK, in April 2014 and to produce a revised and updated consensus statement about its clinical use including technique, data interpretation, relationship with outcome, role in guiding therapy in neurocritical care and research applications. Hutchinson PJ, Jalloh I, Helmy A, Carpenter Keri LH, Rostami E, Bellander BM, et al. Consensus statement from the 2014 International Microdialysis Forum. Intensive Care Med. 2015 Sep;41(9):1517-28. 10.1007/s00134-015-3930-y 1432-1238 0342-4642 Intensive Care Medicine http://hdl.handle.net/20.500.13003/10735 26194024 L605254483 2-s2.0-84940452901 http://hdl.handle.net/20.500.12105/20136 360314900001 Brain chemistry Microdialysis Outcome Subarachnoid hemorrhage Traumatic brain injury Consensus statement from the 2014 International Microdialysis Forum