<?xml version="1.0" encoding="UTF-8"?><?xml-stylesheet type="text/xsl" href="static/style.xsl"?><OAI-PMH xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd"><responseDate>2026-06-14T05:05:24Z</responseDate><request verb="GetRecord" identifier="oai:repisalud.isciii.es:20.500.12105/20116" metadataPrefix="mets">https://repisalud.isciii.es/rest/oai/request</request><GetRecord><record><header><identifier>oai:repisalud.isciii.es:20.500.12105/20116</identifier><datestamp>2024-11-29T07:04:17Z</datestamp><setSpec>com_20.500.12105_15322</setSpec><setSpec>com_20.500.12105_2051</setSpec><setSpec>col_20.500.12105_16967</setSpec></header><metadata><mets xmlns="http://www.loc.gov/METS/" xmlns:doc="http://www.lyncode.com/xoai" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" ID="&#xa;&#x9;&#x9;&#x9;&#x9;DSpace_ITEM_20.500.12105-20116" TYPE="DSpace ITEM" PROFILE="DSpace METS SIP Profile 1.0" xsi:schemaLocation="http://www.loc.gov/METS/ http://www.loc.gov/standards/mets/mets.xsd" OBJID="&#xa;&#x9;&#x9;&#x9;&#x9;hdl:20.500.12105/20116">
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               <mods:name>
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                     <mods:roleTerm type="text">author</mods:roleTerm>
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                  <mods:namePart>Castro, Adoración</mods:namePart>
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               <mods:name>
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                  <mods:namePart>Garcia-Palacios, Azucena</mods:namePart>
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                  <mods:namePart>Garcia-Campayo, Javier</mods:namePart>
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                  <mods:namePart>Mayoral, Fermin</mods:namePart>
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               <mods:name>
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                  <mods:namePart>Botella, Cristina</mods:namePart>
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                  <mods:namePart>Maria Garcia-Herrera, Jose</mods:namePart>
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                  <mods:namePart>Perez-Yus, Mari-Cruz</mods:namePart>
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               <mods:name>
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                  <mods:namePart>Vives, Margalida</mods:namePart>
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                  <mods:namePart>Banos, Rosa M</mods:namePart>
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                  <mods:namePart>Roca, Miquel</mods:namePart>
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               <mods:name>
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                     <mods:roleTerm type="text">author</mods:roleTerm>
                  </mods:role>
                  <mods:namePart>Gili, Margalida</mods:namePart>
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                  <mods:dateAccessioned encoding="iso8601">2024-07-04T12:55:00Z</mods:dateAccessioned>
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                  <mods:dateAvailable encoding="iso8601">2024-07-04T12:55:00Z</mods:dateAvailable>
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                  <mods:dateIssued encoding="iso8601">2015-05-07</mods:dateIssued>
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               <mods:identifier type="citation">Castro Garcia AC, Garcia-Palacios A, Garcia-Campayo J, Mayoral F, Botella C, Garcia-Herrera JM, et al. Efficacy of low-intensity psychological intervention applied by ICTs for the treatment of depression in primary care: a controlled trial. BMC Psychiatry. 2015 May 07;15:106.</mods:identifier>
               <mods:identifier type="doi">10.1186/s12888-015-0475-0</mods:identifier>
               <mods:identifier type="e-issn">1471-244X</mods:identifier>
               <mods:identifier type="journal">BMC Psychiatry</mods:identifier>
               <mods:identifier type="other">http://hdl.handle.net/20.500.13003/10846</mods:identifier>
               <mods:identifier type="pubmedID">25948287</mods:identifier>
               <mods:identifier type="pui">L604327797</mods:identifier>
               <mods:identifier type="scopus">2-s2.0-84929144927</mods:identifier>
               <mods:identifier type="uri">http://hdl.handle.net/20.500.12105/20116</mods:identifier>
               <mods:identifier type="wos">354352100001</mods:identifier>
               <mods:abstract>Background: Depression is one of the most common disorders in Psychiatric and Primary Care settings and is associated with significant disability and economic costs. Low-intensity psychological interventions applied by Information and Communication Technologies (ICTs) could be an efficacious and cost-effective therapeutic option for the treatment of depression. The aim of this study is to assess 3 low-intensity psychological interventions applied by ICTs (healthy lifestyle, positive affect and mindfulness) in Primary Care; significant efficacy for depression treatment has previously showed in specialized clinical settings by those interventions, but ICTs were not used. Method: Multicenter controlled randomized clinical trial in 4 parallel groups. Interventions have been designed and on-line device adaptation has been carried out. Subsequently, the randomized controlled clinical trial will be conducted. A sample of N = 240 mild and moderate depressed patients will be recruited and assessed in Primary Care settings. Patients will be randomly assigned to a) healthy lifestyle psychoeducational program + improved primary care usual treatment (ITAU), b) focused program on positive affect promotion + ITAU c) mindfulness + ITAU or d) ITAU. The intervention format will be one face to face session and four ICTs on-line modules. Patients will be diagnosed with MINI psychiatric interview. Main outcome will be PHQ-9 score. They will be also assessed by SF-12 Health Survey, Client Service Receipt Inventory, EuroQoL-5D questionnaire, Positive and Negative Affect Scale, Five Facet Mindfulness Questionnaire and the Pemberton Happiness Index. Patients will be assessed at baseline, post, 6 and 12 post-treatment months. An intention to treat and per protocol analysis will be performed. Discussion: Low-intensity psychological interventions applied by Information and Communication Technologies have been not used before in Spain and could be an efficacious and cost-effective therapeutic option for depression treatment. The strength of the study is that it is the first multicenter controlled randomized clinical trial of three low intensity and self-guided interventions applied by ICTs (healthy lifestyle psychoeducational program; focused program on positive affect promotion and brief intervention based on mindfulness) in Primary Care settings.</mods:abstract>
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               <mods:subject>
                  <mods:topic>Depression</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Primary health care</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Computer-delivered psychotherapy</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Randomized controlled trial</mods:topic>
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               <mods:titleInfo>
                  <mods:title>Efficacy of low-intensity psychological intervention applied by ICTs for the treatment of depression in primary care: a controlled trial</mods:title>
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               <mods:genre>research article</mods:genre>
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