2026-04-29T04:08:31Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/200862024-11-29T03:05:53Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967
Repisalud
author
Cardoso-de-Mello-e-Mello-Ribeiro, Ana Paula
author
Rodriguez-Blanco, Cleofas
author
Riquelme-Agullo, Inmaculada
author
Marcos Heredia-Rizo, Alberto
author
Ricard, Francois
author
Oliva-Pascual-Vaca, Angel
2024-07-04T12:54:48Z
2024-07-04T12:54:48Z
2015
Cardoso-De-Mello-E-Mello-Ribeiro AP, Rodriguez-Blanco C, Riquelme I, Heredia-Rizo AM, Ricard F, Oliva-Pascual-Vaca A. Effects of the Fourth Ventricle Compression in the Regulation of the Autonomic Nervous System: A Randomized Control Trial. Evid-based Complement Altern Med. 2015;2015:148285. Epub 2015 Jun 14.
1741-427X
http://hdl.handle.net/20.500.13003/10990
http://hdl.handle.net/20.500.12105/20086
26199632
10.1155/2015/148285
1741-4288
Evidence-Based Complementary and Alternative Medicine
2-s2.0-84934343116
357194000001
L605026390
Introduction. Dysfunction of the autonomic nervous system is an important factor in the development of chronic pain. Fourth ventricle compression (CV-4) has been shown to influence autonomic activity. Nevertheless, the physiological mechanisms behind these effects remain unclear. Objectives. This study is aimed at evaluating the effects of fourth ventricle compression on the autonomic nervous system. Methods. Forty healthy adults were randomly assigned to an intervention group, on whom CV-4 was performed, or to a control group, who received a placebo intervention (nontherapeutic touch on the occipital bone). In both groups, plasmatic catecholamine levels, blood pressure, and heart rate were measured before and immediately after the intervention. Results. No effects related to the intervention were found. Although a reduction of norepinephrine, systolic blood pressure, and heart rate was found after the intervention, it was not exclusive to the intervention group. In fact, only the control group showed an increment of dopamine levels after intervention. Conclusion. Fourth ventricle compression seems not to have any effect in plasmatic catecholamine levels, blood pressure, or heart rate. Further studies are needed to clarify the CV-4 physiologic mechanisms and clinical efficacy in autonomic regulation and pain treatment.
eng
Effects of the Fourth Ventricle Compression in the Regulation of the Autonomic Nervous System: A Randomized Control Trial
research article