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oai:repisalud.isciii.es:20.500.12105/200862024-11-29T03:05:53Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967

00925njm 22002777a 4500 dc Cardoso-de-Mello-e-Mello-Ribeiro, Ana Paula author Rodriguez-Blanco, Cleofas author Riquelme-Agullo, Inmaculada author Marcos Heredia-Rizo, Alberto author Ricard, Francois author Oliva-Pascual-Vaca, Angel author 2015 Introduction. Dysfunction of the autonomic nervous system is an important factor in the development of chronic pain. Fourth ventricle compression (CV-4) has been shown to influence autonomic activity. Nevertheless, the physiological mechanisms behind these effects remain unclear. Objectives. This study is aimed at evaluating the effects of fourth ventricle compression on the autonomic nervous system. Methods. Forty healthy adults were randomly assigned to an intervention group, on whom CV-4 was performed, or to a control group, who received a placebo intervention (nontherapeutic touch on the occipital bone). In both groups, plasmatic catecholamine levels, blood pressure, and heart rate were measured before and immediately after the intervention. Results. No effects related to the intervention were found. Although a reduction of norepinephrine, systolic blood pressure, and heart rate was found after the intervention, it was not exclusive to the intervention group. In fact, only the control group showed an increment of dopamine levels after intervention. Conclusion. Fourth ventricle compression seems not to have any effect in plasmatic catecholamine levels, blood pressure, or heart rate. Further studies are needed to clarify the CV-4 physiologic mechanisms and clinical efficacy in autonomic regulation and pain treatment. Cardoso-De-Mello-E-Mello-Ribeiro AP, Rodriguez-Blanco C, Riquelme I, Heredia-Rizo AM, Ricard F, Oliva-Pascual-Vaca A. Effects of the Fourth Ventricle Compression in the Regulation of the Autonomic Nervous System: A Randomized Control Trial. Evid-based Complement Altern Med. 2015;2015:148285. Epub 2015 Jun 14. 1741-427X http://hdl.handle.net/20.500.13003/10990 http://hdl.handle.net/20.500.12105/20086 26199632 10.1155/2015/148285 1741-4288 Evidence-Based Complementary and Alternative Medicine 2-s2.0-84934343116 357194000001 L605026390 Effects of the Fourth Ventricle Compression in the Regulation of the Autonomic Nervous System: A Randomized Control Trial