<?xml version="1.0" encoding="UTF-8"?><?xml-stylesheet type="text/xsl" href="static/style.xsl"?><OAI-PMH xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd"><responseDate>2026-05-22T11:08:16Z</responseDate><request verb="GetRecord" identifier="oai:repisalud.isciii.es:20.500.12105/20025" metadataPrefix="mets">https://repisalud.isciii.es/rest/oai/request</request><GetRecord><record><header><identifier>oai:repisalud.isciii.es:20.500.12105/20025</identifier><datestamp>2024-11-28T21:09:04Z</datestamp><setSpec>com_20.500.12105_15322</setSpec><setSpec>com_20.500.12105_2051</setSpec><setSpec>col_20.500.12105_16967</setSpec></header><metadata><mets xmlns="http://www.loc.gov/METS/" xmlns:doc="http://www.lyncode.com/xoai" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" ID="&#xa;&#x9;&#x9;&#x9;&#x9;DSpace_ITEM_20.500.12105-20025" TYPE="DSpace ITEM" PROFILE="DSpace METS SIP Profile 1.0" xsi:schemaLocation="http://www.loc.gov/METS/ http://www.loc.gov/standards/mets/mets.xsd" OBJID="&#xa;&#x9;&#x9;&#x9;&#x9;hdl:20.500.12105/20025">
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                  <mods:namePart>Cassinello, J.</mods:namePart>
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                  <mods:namePart>Climent, M. A.</mods:namePart>
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                  <mods:namePart>Gonzalez Del Alba, Aranzazu</mods:namePart>
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                  <mods:namePart>Mellado, B.</mods:namePart>
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                  <mods:namePart>Virizuela, J. A.</mods:namePart>
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                  <mods:dateAccessioned encoding="iso8601">2024-07-03T11:09:40Z</mods:dateAccessioned>
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               <mods:identifier type="citation">Cassinello J, Climent MA, Gonzalez Del Alba A, Mellado B, Virizuela JA. SEOM Clinical guidelines for the treatment of metastatic prostate cancer. Clin Transl Oncol. 2014 Dec;16(12):1060-6. Epub 2014 Oct 16.</mods:identifier>
               <mods:identifier type="doi">10.1007/s12094-014-1225-3</mods:identifier>
               <mods:identifier type="e-issn">1699-3055</mods:identifier>
               <mods:identifier type="issn">1699-048X</mods:identifier>
               <mods:identifier type="journal">Clinical &amp; Translational Oncology</mods:identifier>
               <mods:identifier type="other">http://hdl.handle.net/20.500.13003/11050</mods:identifier>
               <mods:identifier type="pubmedID">25319721</mods:identifier>
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               <mods:abstract>Androgen deprivation treatment is the current standard first-line treatment for metastatic prostate cancer. For several years, docetaxel was the only treatment with a proven survival benefit for castration-resistant prostate cancer (CRPC). Since docetaxel became standard of care for men with symptomatic metastatic castration-resistant prostate cancer (CRPC), three treatment virtual spaces, for treatment and drug development in CPRC, have emerged: pre-docetaxel, docetaxel combinations and post-docetaxel. Sipuleucel-T, cabazitaxel, abiraterone, enzalutamide and radium-223 have been approved in the pre- or post-docetaxel setting in metastatic CRPC during the last few years. Patients are now living longer and experiencing better quality of life. Strategies for patient selection and treatment sequencing are therefore urgently required.</mods:abstract>
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                  <mods:topic>Androgen deprivation treatment</mods:topic>
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                  <mods:topic>Castration-resistant prostate cancer</mods:topic>
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                  <mods:topic>Docetaxel</mods:topic>
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                  <mods:topic>Cabacitaxel</mods:topic>
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                  <mods:topic>Abiraterone</mods:topic>
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                  <mods:topic>Enzalutamide</mods:topic>
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               <mods:subject>
                  <mods:topic>Radium 223</mods:topic>
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                  <mods:title>SEOM Clinical guidelines for the treatment of metastatic prostate cancer</mods:title>
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