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oai:repisalud.isciii.es:20.500.12105/200152024-11-29T02:31:31Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967

00925njm 22002777a 4500 dc Mejia-Lancheros, Cilia author Estruch, Ramon author Martinez-Gonzalez, Miguel-Angel author Salas-Salvado, Jordi author Castaner, Olga author Corella, Dolores author Aros, Fernando author Gomez-Gracia, Enrique author Fiol Sala, MiquelAutor/a del sistema sanitario público de las Islas Baleares Orcid author Lapetra, Jose author Serra-Majem, Lluis author Pinto, Xavier author Ros, Emilio author Díez-Espino, Javier author Basora, Josep author Sorli, Jose-V author Lamuela-Raventos, Rosa-Maria author Ruiz-Gutierrez, Valentina author Munoz, Miguel-Angel author PREDIMED Study Investigators author 2014-10-03 Background: Whilst it is well known that psychosocial determinants may contribute to cardiovascular diseases (CVD), data from specific groups are scarce. The present study aims to determine the contribution of psychosocial determinants in increasing the risk of cardiovascular events (myocardial infarction and stroke), and death from CVD, in a high risk adult population. Methods: Longitudinal prospective study of 7263 patients (57.5% women), mean age 67.0 (SD 6.2) free from CVD but at high risk, with a median follow-up of 4.8 years (from October 2003 to December 2010). The Hazard Ratios (HRs) of cardiovascular events (myocardial infarction, stroke, and death from cardiovascular causes) related to educational attainment, diagnosed depression (based on medical records), and low social support (number of people living in the household) were estimated by multivariate Cox regression models. Results: Stroke incidence was associated with low educational level in the whole population (HR: 1.83, 95% CI: 1.09-3.09), and especially in men (HR: 2.11, 95% CI 1.09-4.06). Myocardial infarction and CVD mortality were not associated with any of the psychosocial factors considered. Conclusion: Adults with low educational level had a higher risk of stroke. Depression and low social support were not associated with CVD incidence. Mejia-Lancheros C, Estruch R, Martinez-Gonzalez MA, Salas-Salvado J, Castaner O, Corella D, et al. Impact of psychosocial factors on cardiovascular morbimortality: a prospective cohort study. BMC Cardiovasc Disord. 2014 Oct 03;14:135. 10.1186/1471-2261-14-135 1471-2261 BMC Cardiovascular Disorders http://hdl.handle.net/20.500.13003/11100 25280390 L600191988 2-s2.0-84908079835 http://hdl.handle.net/20.500.12105/20015 343258200001 Stroke Acute myocardial infarction Cardiovascular death Educational level Socioeconomic position Depression Social support Health inequalities Impact of psychosocial factors on cardiovascular morbimortality: a prospective cohort study