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oai:repisalud.isciii.es:20.500.12105/200102024-11-29T01:50:54Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967

00925njm 22002777a 4500 dc Sabater, Sebastia author Berenguer, Roberto author Honrubia-Gomez, Paloma author Rivera, Miguel author Nunez, Ana author Jiménez-Jiménez, Esther author Martos, Ana author Ramirez-Castillejo, Carmen author 2014-09 Radiation of experimental culture cells on plates with various wells can cause a risk of underdosage as a result of the existence of multiple air-water interfaces. The objective of our study was to quantify this error in culture plates with multiple wells. Radiation conditions were simulated with the GAMOS code, based on the GEANT4 code, and this was compared with a simulation performed with PENELOPE and measured data. We observed a slight underdosage of similar to 4% on the most superficial half of the culture medium. We believe that this underdosage does not have a significant effect on the dose received by culture cells deposited in a monolayer and adhered to the base of the wells. Sabater S, Berenguer R, Honrubia-Gomez P, Rivera M, Nunez A, Jimenez-Jimenez E, et al. How air influences radiation dose deposition in multiwell culture plates: a Monte Carlo simulation of radiation geometry. J Radiat Res. 2014 Sep;55(5):1009-14. Epub 2014 Apr 10. 10.1093/jrr/rru022 1349-9157 0449-3060 Journal of Radiation Research http://hdl.handle.net/20.500.13003/11135 24722683 L605507452 2-s2.0-84908155004 http://hdl.handle.net/20.500.12105/20010 342223100021 Monte Carlo Plate irradiation Culture cells How air influences radiation dose deposition in multiwell culture plates: a Monte Carlo simulation of radiation geometry