2026-04-29T11:10:09Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/199822024-11-28T20:07:16Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967

00925njm 22002777a 4500 dc Grases, Felix author Rodríguez, Adrián author Berga, Francisco author Costa-Bauza, Antonia author Maria Prieto, Rafael author Burdallo, Isabel author Cadarso, Alfredo author Jimenez-Jorquera, Cecilia author Baldi, Antonio author Garganta, Rosendo author 2014-04-28 Purpose: Urinary pH is an important factor linked to renal stone disease and a useful marker in the treatment of urolithiasis. Although the gold standard for measuring urinary pH utilizes a glass electrode and a pH meter, at present dipstick testing is largely used to estimate urinary pH. However, the accuracy and precision of this method may be insufficient for making clinical decisions in patients with lithiasis. The aim of this study is to describe a new device for urinary pH testing. Methods: The device includes a pH sensor based on differential measurement of an ISFET-REFET pair. The drawbacks associated with this type of configuration, namely short lifetime and manual fabrication, have been overcome in the prototype. An automatic one point calibration is performed when turning on the system. Two buffer solutions were utilized to determine the intra-and inter-day precision of the device. The pH of 30 fresh human urine samples was measured using a pH-meter, a dipstick and the new electronic device. Results: In some cases, dipstick measurements differed from those of the pH meter by more than 0.40 units, a clinically relevant discrepancy, whereas none of the measurements made with the new electronic device differed from the results of the pH-meter by more than 0.1 pH units. Conclusions: This new electronic device has the possibility to be used by stone-formers to control their urinary pH at home, increasing the tools available for stone prevention and prophylaxis. Grases F, Rodriguez A, Berga Montaner F, Costa-Bauza A, Prieto RM, Burdallo I, et al. A new device for simple and accurate urinary pH testing by the Stone-former patient. SpringerPlus. 2014 Apr 28;3:209. 10.1186/2193-1801-3-209 2193-1801 Springerplus http://hdl.handle.net/20.500.13003/11272 24839588 2-s2.0-84903940000 http://hdl.handle.net/20.500.12105/19982 359025800005 Urinary pH Renal lithiasis pH measurement pH self-control A new device for simple and accurate urinary pH testing by the Stone-former patient