2026-07-23T17:50:17Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/198022024-11-21T16:51:37Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
Repisalud
author
Miguel-Vicedo, Mariola
author
Cabello, Paula
author
Ortega-Navas, M Carmen
author
Gonzalez-Barrio, David
author
Fuentes Corripio, Isabel
funder
Instituto de Salud Carlos III
funder
Ministerio de Economía y Competitividad (España)
2024-06-19T13:45:42Z
2024-06-19T13:45:42Z
2024-06-12
J Epidemiol Glob Health. 2024 Sep;14(3):621-637.
10.1007/s44197-024-00258-w
2210-6014
Journal of epidemiology and global health
38864976
http://hdl.handle.net/20.500.12105/19802
Humans are infected by Toxoplasma gondii worldwide and its consequences may seriously affect an immune deprived population such as HIV and transplanted patients or pregnant women and foetuses. A deep knowledge of toxoplasmosis seroprevalence in Spain is needed in order to better shape health policies and educational programs. We present the results of the first systematic review and meta-analysis on the human prevalence for this disease in Spain. Databases (PubMed, Web of Science, SCOPUS and Teseo) were searched for relevant studies that were published between January 1993 and December 2023 and all population-based cross-sectional and longitudinal studies reporting the human seroprevalence in Spain were revised. Within the population analysed, our targeted groups were immunocompetent population, pregnant women and immunocompromised patients. Among 572 studies and 35 doctoral theses retrieved, 15 studies and three doctoral theses were included in the meta-analysis. A random effects model was used for the meta-analyses due to the high heterogeneity found between studies (I2: 99.97), since it is a statistically conservative model, in addition to allowing better external validity. The global pooled seroprevalence was 32.3% (95% CI 28.7-36.2%). Most of the studies carried out were in pregnant women and the meta-analysis reported that the pooled seroprevalence of toxoplasmosis in pregnant women in Spain was 24.4% (24,737/85,703, 95% CI 21.2-28.0%), based on the random effects model. It is recommended to continue monitoring the seroprevalence status of T. gondii in order to obtain essential guidelines for the prevention and control of the infection in the population.
eng
Toxoplasma gondii
Toxoplasmosis
Prevalence
Seroprevalence
Spain
Human
HIV patient
Cerebral toxoplasmosis
Pregnant woman
Prevalence of Human Toxoplasmosis in Spain Throughout the Three Last Decades (1993-2023): A Systematic Review and Meta-analysis
review article
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PrevalenceHumanToxoplasmosisSpain_2024.pdf
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Supplementary_PrevalenceHumanToxoplasmosisSpain_2024.pdf
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PrevalenceHumanToxoplasmosisSpain_2024.pdf.txt
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