2026-04-29T06:15:41Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/193682024-09-27T09:41:58Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19605
Repisalud
author
Paternina-Die, María
author
Martínez-García, Magdalena
author
Martín de Blas, Daniel
author
Noguero, Inés
author
Servin-Barthet, Camila
author
Pretus, Clara
author
Soler, Anna
author
López-Montoya, Gonzalo
author
Desco, Manuel
author
Carmona, Susana
funder
Ministerio de Ciencia, Innovación y Universidades (España)
funder
Fundación La Caixa
funder
Unión Europea. Comisión Europea. European Research Council (ERC)
funder
Unión Europea. Comisión Europea. H2020
funder
Centro Nacional de Investigaciones Cardiovasculares Carlos III (España)
funder
Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)
2024-05-10T14:45:12Z
2024-05-10T14:45:12Z
2024-02
Nat Neurosci. 2024 Feb;27(2):319-327.
http://hdl.handle.net/20.500.12105/19368
38182834
10.1038/s41593-023-01513-2
1546-1726
Nature neuroscience
Pregnancy is a unique neuroplastic period in adult life. This longitudinal study tracked brain cortical changes during the peripartum period and explored how the type of childbirth affects these changes. We collected neuroanatomic, obstetric and neuropsychological data from 110 first-time mothers during late pregnancy and early postpartum, as well as from 34 nulliparous women evaluated at similar time points. During late pregnancy, mothers showed lower cortical volume than controls across all functional networks. These cortical differences attenuated in the early postpartum session. Default mode and frontoparietal networks showed below-expected volume increases during peripartum, suggesting that their reductions may persist longer. Results also pointed to different cortical trajectories in mothers who delivered by scheduled C-section. The main findings were replicated in an independent sample of 29 mothers and 24 nulliparous women. These data suggest a dynamic trajectory of cortical decreases during pregnancy that attenuates in the postpartum period, at a different rate depending on the brain network and childbirth type.
eng
Women's neuroplasticity during gestation, childbirth and postpartum.
journal article
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https://repisalud.isciii.es/bitstreams/70ce50ec-be07-4b6b-888d-fe7f9657ab48/download
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Women’s neuroplasticity during gestation_Nat Neurosci_2024.pdf
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https://repisalud.isciii.es/bitstreams/c63d5362-be1e-411a-bf25-39e09dffbe99/download
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Women’s neuroplasticity during gestation_Nat Neurosci_2024.pdf.txt