2026-05-17T01:18:39Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/190102025-04-23T08:12:42Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609

00925njm 22002777a 4500 dc López-Herrero, R author Sánchez-de Prada, L author Tamayo-Velasco, A author Heredia-Rodríguez, María author Bardají Carrillo, M author Jorge Monjas, P author de la Varga-Martínez, O author Resino, Salvador author Sarmentero-López de Quintana, G author Gómez-Sánchez, E author Tamayo, E author 2024-03-03 We realize a nationwide population-based retrospective study to analyze the characteristics and risk factors of fungal co-infections in COVID-19 hospitalized patients as well as describe their causative agents in the Spanish population in 2020 and 2021. Data were obtained from records in the Minimum Basic Data Set of the National Surveillance System for Hospital Data in Spain, provided by the Ministry of Health, and annually published with two years lag. The assessment of the risk associated with the development of healthcare-associated fungal co-infections was assessed using an adjusted logistic regression model. The incidence of fungal co-infection in COVID-19 hospitalized patients was 1.41%. The main risk factors associated were surgery, sepsis, age, male gender, obesity, and COPD. Co-infection was associated with worse outcomes including higher in-hospital and in ICU mortality, and higher length of stay. Candida spp. and Aspergillus spp. were the microorganisms more frequent. This is the first study analyzing fungal coinfection at a national level in hospitalized patients with COVID-19 in Spanish population and one of the few studies available that demonstrate that surgery was an independent risk factor of Aspergillosis coinfection in COVID-19 patients. Sci Rep. 2024 Mar 3;14(1):5203. 10.1038/s41598-024-54340-1 2045-2322 Scientific reports 38433130 http://hdl.handle.net/20.500.12105/19010 COVID-19 Fungal infection Spain Hospitalization Epidemiology of fungal infection in COVID 19 in Spain during 2020 and 2021: a nationwide study