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oai:repisalud.isciii.es:20.500.12105/189972025-04-24T10:33:23Zcom_20.500.12105_2052com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19608col_20.500.12105_16959col_20.500.12105_16988

00925njm 22002777a 4500 dc Gómrez Del Río, Sergio author Plans-Beriso, Elena author Ramis, Rebeca author Ortolá, Rosario author Pastor-Barriuso, Roberto author Sotos-Prieto, Mercedes author Castelló Pastor, Adela author Olmedo-Requena, Rocío author Jimenez-Moleon, Jose J. author Fernández Félix, Borja María author Muriel, Alfonso author Miret, Marta author Ayuso-Mateos, José Luis author Choi, Yoon-Hyeong author Rodríguez-Artalejo, Fernando author Fernandez-Navarro, Pablo L author García-Esquinas, Esther author 2024-02-01 Background: Traffic exposure has been associated with biomarkers of increased biological ageing, age-related chronic morbidities, and increased respiratory, cardiovascular, and all-cause mortality. Whether it is associated with functional impairments and unhealthy ageing trajectories is unknown. Methods: Nationally representative population-based cohort with 3,126 community-dwelling individuals aged ≥60 years who contributed 8,291 biannual visits over a 10 year period. Unhealthy ageing was estimated with a deficit accumulation index (DAI) based on the number and severity of 52 health deficits, including 22 objectively-measured impairments in physical and cognitive functioning. Differences in DAI at each follow-up across quintiles of residential traffic density (RTD) at 50 and 100 meters, and closest distance to a petrol station, were estimated using flexible marginal structural models with inverse probability of censoring weights. Models were adjusted for sociodemographic and time-varying lifestyle factors, social deprivation index at the census tract and residential exposure to natural spaces. Results: At baseline, the mean (SD) age and DAI score of the participants were 69.0 (6.6) years and 17.02 (11.0) %, and 54.0% were women. The median (IQR) RTD at 50 and 100 meters were 77 (31-467) and 509 (182-1802) vehicles/day, and the mean (SD) distance to the nearest petrol station of 962 (1317) meters. The average increase in DAI (95%CI) for participants in quintiles Q2-Q5 (vs Q1) of RTD at 50 meters was of 1.51 (0.50, 2.53), 0.98 (-0.05, 2.01), 2.20 (1.18, 3.21) and 1.98 (0.90, 3.05), respectively. Consistent findings were observed at 100 meters. By domains, most of the deficits accumulated with increased RTD were of a functional nature, although RTD at 50 meters was also associated with worse self-reported health, increased vitality problems and higher incidence of chronic morbidities. Living closer to a petrol station was associated with a higher incidence of functional impairments and chronic morbidities. Conclusions: Exposure to nearby residential traffic is associated with accelerated trajectories of unhealthy ageing. Diminishing traffic pollution should become a priority intervention for adding healthy years to life in the old age. Environ Health. 2024 Feb 1;23(1):15. 10.1186/s12940-024-01057-3 1476-069X Environmental health : a global access science source 38303067 http://hdl.handle.net/20.500.12105/18997 Trafc pollution Unhealthy ageing Frailty Exposure to residential traffic and trajectories of unhealthy ageing: results from a nationally-representative cohort of older adults