2026-06-14T05:05:26Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/189652024-11-29T18:54:20Zcom_20.500.12105_2173com_20.500.12105_2051col_20.500.12105_19597
Repisalud
author
Murga, Matilde
author
Fernandez-Capetillo, Oscar
funder
European Union (EU)
funder
Ministerio de Ciencia e Innovación (España)
funder
Asociación Española Contra el Cáncer
funder
Swedish Research Council
funder
Swedish Cancer Society (Cancerfonden)
2024-03-15T11:12:19Z
2024-03-15T11:12:19Z
2022-11
Mol Oncol . 2022 ;16(21):3757-3760.
10.1002/1878-0261.13325
1878-0261
Molecular oncology
36321722
http://hdl.handle.net/20.500.12105/18965
These are exciting times to be involved in biomedical research. The transition from a scientific hypothesis to a testable therapy is now faster than ever, and new technologies that facilitate drug development are constantly emerging. The rapid development of COVID-19 vaccines provides a clear example of the current pace of drug discovery and its clinical implementation. Importantly, the wide availability of technologies that speed up drug development has also reached oncology, and investigators can now consider several independent strategies when looking to develop a new therapy. This thematic issue provides an overview of recent advances in cancer drug discovery, in areas such as fragment-based drug development, targeting the DNA damage response or the MYC oncogene, senolytic therapies and computational tools that facilitate drug discovery and the selection of treatments in personalized medicine. We are confident that reading these reviews will help those interested in the development of cancer therapies get a broader and updated view of available opportunities and challenges.
eng
Emerging concepts in drug discovery for cancer therapy.
journal article
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URL
https://repisalud.isciii.es/bitstreams/206d8ca7-ab6e-4ad8-8535-066a670ffc4b/download
File
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application/pdf
Emergingconceptsindrugdiscovery_2022.pdf
URL
https://repisalud.isciii.es/bitstreams/f6b7bf86-84e1-4d7b-ba8b-176a390c88ce/download
File
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Emergingconceptsindrugdiscovery_2022.pdf.txt