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oai:repisalud.isciii.es:20.500.12105/188072024-02-27T15:16:25Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16927col_20.500.12105_16981

00925njm 22002777a 4500 dc Orozco-Beltrán, Domingo author Merino-Torres, Juan Francisco author Pérez, Antonio author Cebrián-Cuenca, Ana M author Párraga-Martínez, Ignacio author Ávila-Lachica, Luis author Rojo-Martínez, Gemma author Pomares-Gómez, Francisco J author Álvarez-Guisasola, Fernando author Sánchez-Molla, Manuel author Gutiérrez, Felix author Ortega, Francisco J author Mata-Cases, Manel author Carretero-Anibarro, Enrique author Vilaseca, Josep Maria author Quesada, Jose A author 2022-04-08 The purpose of this study was to identify clinical, analytical, and sociodemographic variables associated with the need for hospital admission in people over 50 years infected with SARS-CoV-2 and to assess whether diabetes mellitus conditions the risk of hospitalization. A multicenter case-control study analyzing electronic medical records in patients with COVID-19 from 1 March 2020 to 30 April 2021 was conducted. We included 790 patients: 295 cases admitted to the hospital and 495 controls. Under half (n = 386, 48.8%) were women, and 8.5% were active smokers. The main comorbidities were hypertension (50.5%), dyslipidemia, obesity, and diabetes (37.5%). Multivariable logistic regression showed that hospital admission was associated with age above 65 years (OR from 2.45 to 3.89, ascending with age group); male sex (OR 2.15, 95% CI 1.47-3.15), fever (OR 4.31, 95% CI 2.87-6.47), cough (OR 1.89, 95% CI 1.28-2.80), asthenia/malaise (OR 2.04, 95% CI 1.38-3.03), dyspnea (4.69, 95% CI 3.00-7.33), confusion (OR 8.87, 95% CI 1.68-46.78), and a history of hypertension (OR 1.61, 95% CI 1.08-2.41) or immunosuppression (OR 4.97, 95% CI 1.45-17.09). Diabetes was not associated with increased risk of hospital admission (OR 1.18, 95% CI 0.80-1.72; p = 0.38). Diabetes did not increase the risk of hospital admission in people over 50 years old, but advanced age, male sex, fever, cough, asthenia, dyspnea/confusion, and hypertension or immunosuppression did. 2077-0383 http://hdl.handle.net/10668/21266 http://hdl.handle.net/20.500.12105/18807 35456185 10.3390/jcm11082092 Journal of clinical medicine COVID-19 hospitalization obesity and diabetes mellitus type 2 primary care research Diabetes Does Not Increase the Risk of Hospitalization Due to COVID-19 in Patients Aged 50 Years or Older in Primary Care-APHOSDIAB-COVID-19 Multicenter Study.