<?xml version="1.0" encoding="UTF-8"?><?xml-stylesheet type="text/xsl" href="static/style.xsl"?><OAI-PMH xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd"><responseDate>2026-08-29T12:39:10Z</responseDate><request verb="GetRecord" identifier="oai:repisalud.isciii.es:20.500.12105/18793" metadataPrefix="mets">https://repisalud.isciii.es/rest/oai/request</request><GetRecord><record><header><identifier>oai:repisalud.isciii.es:20.500.12105/18793</identifier><datestamp>2024-09-21T19:05:03Z</datestamp><setSpec>com_20.500.12105_15322</setSpec><setSpec>com_20.500.12105_2051</setSpec><setSpec>col_20.500.12105_16927</setSpec><setSpec>col_20.500.12105_16970</setSpec></header><metadata><mets xmlns="http://www.loc.gov/METS/" xmlns:doc="http://www.lyncode.com/xoai" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" ID="&#xa;&#x9;&#x9;&#x9;&#x9;DSpace_ITEM_20.500.12105-18793" TYPE="DSpace ITEM" PROFILE="DSpace METS SIP Profile 1.0" xsi:schemaLocation="http://www.loc.gov/METS/ http://www.loc.gov/standards/mets/mets.xsd" OBJID="&#xa;&#x9;&#x9;&#x9;&#x9;hdl:20.500.12105/18793">
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                  <mods:namePart>Fernández-Montes, Ana</mods:namePart>
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                  <mods:namePart>Alcaide, Julia</mods:namePart>
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                  <mods:namePart>Alsina, María</mods:namePart>
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                  <mods:namePart>Custodio, Ana Belén</mods:namePart>
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                  <mods:namePart>Franco, Lourdes Fernández</mods:namePart>
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                  <mods:namePart>Gallego Plazas, Javier</mods:namePart>
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                  <mods:namePart>Gómez-Martín, Carlos</mods:namePart>
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                  <mods:namePart>Richart, Paula</mods:namePart>
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                  <mods:namePart>Rivera, Fernando</mods:namePart>
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                  <mods:namePart>Martin-Richard, Marta</mods:namePart>
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                  <mods:dateAccessioned encoding="iso8601">2024-02-27T15:16:12Z</mods:dateAccessioned>
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                  <mods:dateIssued encoding="iso8601">2022-03-26</mods:dateIssued>
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               <mods:identifier type="doi">10.1007/s12094-022-02801-2</mods:identifier>
               <mods:identifier type="e-issn">1699-3055</mods:identifier>
               <mods:identifier type="journal">Clinical &amp; translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico</mods:identifier>
               <mods:identifier type="other">http://hdl.handle.net/10668/21075</mods:identifier>
               <mods:identifier type="pubmedID">35347573</mods:identifier>
               <mods:identifier type="uri">http://hdl.handle.net/20.500.12105/18793</mods:identifier>
               <mods:abstract>Esophageal cancer is an aggressive tumor, and is the sixth-leading cause of death from cancer. Incidence is rising in Spain, particularly among men. Two main pathological different subtypes have been described: squamous cell carcinoma and adenocarcinoma. Growing evidence of their epidemiology and molecular differences explains their different response to novel treatments, and they are therefore likely to be treated as two separate entities in the near future. The best results are obtained with a multidisciplinary therapeutic strategy, and the introduction of immunotherapy is a promising new approach that will improve prognosis. In these guidelines, we review the evidence for the different methods of diagnosis and therapeutic strategies that form the basis of our standard of care.</mods:abstract>
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                  <mods:topic>Diagnosis</mods:topic>
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                  <mods:topic>Esophageal cancer</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Treatment</mods:topic>
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               <mods:titleInfo>
                  <mods:title>SEOM-GEMCAD-TTD Clinical Guideline for the diagnosis and treatment of esophageal cancer (2021).</mods:title>
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