2026-04-29T04:09:25Zhttps://repisalud.isciii.es/rest/oai/request
oai:repisalud.isciii.es:20.500.12105/187372024-02-27T15:10:16Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16927col_20.500.12105_16980
Repisalud author Martínez-Vergara, Adrián author Girón Moreno, Rosa Mª author Olveira, Casilda author Victoria Girón, María author Peláez, Adrián author Ancochea, Julio author Oscullo, Grace author Martínez-García, Miguel Ángel 2024-02-27T15:10:16Z 2024-02-27T15:10:16Z 2022-08-12 2079-6382 http://hdl.handle.net/10668/20763 http://hdl.handle.net/20.500.12105/18737 36009967 10.3390/antibiotics11081096 Antibiotics (Basel, Switzerland) Infection by SARS-CoV-2 has unquestionably had an impact on the health of patients with chronic respiratory airway diseases, such as COPD and asthma, but little information is available about its impact on patients with bronchiectasis. The objective of the present study was to analyze the effect of the SARS-CoV-2 pandemic on the state of health, characteristics, and clinical severity (including the number and severity of exacerbations) of patients with non-cystic fibrosis bronchiectasis. This study was multicenter, observational, and ambispective (with data collected before and during the SARS-CoV-2 pandemic), and included 150 patients diagnosed with non-cystic fibrosis bronchiectasis. A significant drop was observed in the number and severity of the exacerbations (57% in all exacerbations and 50% in severe exacerbations) in the E-FACED and BSI multidimensional scores, in the pandemic, compared with the pre-pandemic period. There was also a drop in the percentage of sputum samples positive for pathogenic microorganisms in general (from 58% to 44.7%) and, more specifically, Pseudomonas aeruginosa (from 23.3% to 13.3%) and Haemophilus influenzae (from 21.3% to 14%). During the SARS-CoV-2 period, a significant reduction was observed in the exacerbations, severity, and isolations of pathogenic microorganisms in patients with bronchiectasis. eng BSI COVID-19 E-FACED Haemophilus influenza Pseudomonas aeruginosa SARS-CoV-2 bronchiectasis exacerbation pandemic Impact of the SARS-CoV-2 Virus Pandemic on Patients with Bronchiectasis: A Multicenter Study. research article