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00925njm 22002777a 4500 dc Cano-Ibáñez, Naomi author Serra-Majem, Lluis author Martín-Peláez, Sandra author Martínez-González, Miguel Ángel author Salas-Salvadó, Jordi author Corella, Dolores author Lassale, Camille author Martínez, Jose Alfredo author Alonso-Gómez, Ángel M author Wärnberg, Julia author Vioque, Jesús author Romaguera, Dora author López-Miranda, José author Estruch, Ramon author Gómez-Pérez, Ana María author Lapetra, José author Fernández-Aranda, Fernando author Bueno-Cavanillas, Aurora author Tur, Josep A author Cubelos, Naiara author Pintó, Xavier author Gaforio, José Juan author Matía-Martín, Pilar author Vidal, Josep author Calderón, Cristina author Daimiel, Lidia author Ros, Emilio author Gea, Alfredo author Babio, Nancy author Gimenez-Alba, Ignacio Manuel author Zomeño-Fajardo, María Dolores author Abete, Itziar author Tojal Sierra, Lucas author Romero-Galisteo, Rita P author García de la Hera, Manoli author Martín-Padillo, Marian author García-Ríos, Antonio author Casas, Rosa M author Fernández-García, José Carlos author Santos-Lozano, José Manuel author Toledo, Estefanía author Becerra-Tomas, Nerea author Sorli, Jose V author Schröder, Helmut author Zulet, María A author Sorto-Sánchez, Carolina author Diez-Espino, Javier author Gómez-Martínez, Carlos author Fitó, Montse author Sánchez-Villegas, Almudena author 2022-07-19 Objective: To examine the cross-sectional and longitudinal (2-year follow-up) associations between dietary diversity (DD) and depressive symptoms. Design: An energy-adjusted dietary diversity score (DDS) was assessed using a validated FFQ and was categorised into quartiles (Q). The variety in each food group was classified into four categories of diversity (C). Depressive symptoms were assessed with Beck Depression Inventory-II (Beck II) questionnaire and depression cases defined as physician-diagnosed or Beck II >= 18. Linear and logistic regression models were used. Setting: Spanish older adults with metabolic syndrome (MetS). Participants: A total of 6625 adults aged 55-75 years from the PREDIMED-Plus study with overweight or obesity and MetS. Results: Total DDS was inversely and statistically significantly associated with depression in the cross-sectional analysis conducted; OR Q4 v. Q1 = 0·76 (95 % CI (0·64, 0·90)). This was driven by high diversity compared to low diversity (C3 v. C1) of vegetables (OR = 0·75, 95 % CI (0·57, 0·93)), cereals (OR = 0·72 (95 % CI (0·56, 0·94)) and proteins (OR = 0·27, 95 % CI (0·11, 0·62)). In the longitudinal analysis, there was no significant association between the baseline DDS and changes in depressive symptoms after 2 years of follow-up, except for DD in vegetables C4 v. C1 = (β = 0·70, 95 % CI (0·05, 1·35)). Conclusions: According to our results, DD is inversely associated with depressive symptoms, but eating more diverse does not seem to reduce the risk of future depression. Additional longitudinal studies (with longer follow-up) are needed to confirm these findings. Cano-Ibáñez N, Serra-Majem L, Martín-Peláez S, Martínez-González MÁ, Salas-Salvadó J, Corella D, et al. Dietary diversity and depression: cross-sectional and longitudinal analyses in Spanish adult population with metabolic syndrome. Findings from PREDIMED-Plus trial. Public Health Nutr. 2022 Jul 19;1-13. 10.1017/S1368980022001525 1475-2727 Public health nutrition http://hdl.handle.net/10668/22582 http://hdl.handle.net/20.500.13003/18139 35850714 L638530316 2-s2.0-85131420348 http://hdl.handle.net/20.500.12105/18717 836477900001 Depression Dietary diversity score PREDIMED-Plus study Dietary diversity and depression: cross-sectional and longitudinal analyses in Spanish adult population with metabolic syndrome. Findings from PREDIMED-Plus trial