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oai:repisalud.isciii.es:20.500.12105/185882024-09-21T21:43:23Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16927col_20.500.12105_16982

00925njm 22002777a 4500 dc Guerrero-Orriach, José Luis author Carmona-Luque, Maria Dolores author Gonzalez-Alvarez, Laura author 2022-01-25 Heart disease requires a surgical approach sometimes. Cardiac-surgery patients develop heart failure associated with ischemia induced during extracorporeal circulation. This complication could be decreased with anesthetic drugs. The cardioprotective effects of halogenated agents are based on pre- and postconditioning (sevoflurane, desflurane, or isoflurane) compared to intravenous hypnotics (propofol). We tried to put light on the shadows walking through the line of the halogenated anesthetic drugs' effects in several enzymatic routes and oxidative stress, waiting for the final results of the ACDHUVV-16 clinical trial regarding the genetic modulation of this kind of drugs. http://hdl.handle.net/10668/21137 http://hdl.handle.net/20.500.12105/18588 35163284 10.3390/ijms23031360 1422-0067 International journal of molecular sciences ACDHUVV-16 halogenated heart failure postconditioning preconditioning Heart Failure after Cardiac Surgery: The Role of Halogenated Agents, Myocardial Conditioning and Oxidative Stress.