2026-05-22T00:01:40Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/185192024-11-28T15:36:25Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16938col_20.500.12105_16927
Repisalud
author
Paris, Juan L.
author
de la Torre, Paz
author
Flores, Ana I.
authoraffiliation
[Paris,JL] Allergy Research Group, Instituto de Investigación Biomédica de Málaga-IBIMA, Málaga, Spain. [Paris,JL] Andalusian Centre for Nanomedicine and Biotechnology-BIONAND, Málaga, Spain. [de la Torre,P; Flores,AI] Grupo de Medicina Regenerativa, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain.
2024-02-19T15:32:22Z
2024-02-19T15:32:22Z
2021-12-14
10.3390/pharmaceutics13122149
1999-4923
Pharmaceutics
http://hdl.handle.net/10668/4125
34959429
http://hdl.handle.net/20.500.12105/18519
Allergy constitutes a major health issue due to its large prevalence. The established therapeutic approaches (allergen avoidance, antihistamines, and corticosteroids) do not address the underlying causes of the pathology, highlighting the need for other long-term treatment options. Antigen-specific immunotherapy enables the long-term control of allergic diseases by promoting immunological tolerance to the allergen. However, efficacious immunotherapies are not available for all possible allergens, and the risk of undesired reactions during therapy remains a concern, especially in patients with severe allergic reactions. In this context, two types of therapeutic strategies appear especially promising for the future in the context of allergy: cell therapy and bio- or nano-material-based therapy. In this review, the main strategies developed this far in these two types of strategies are discussed, with several examples illustrating the different approaches.
eng
Allergy
Cell therapy
Biomaterials
Nano-materials
Immunotherapy
Alergia e inmunología
Tratamiento basado en trasplante de células y tejidos
Materiales biocompatibles
Nanoestructuras
Inmunoterapia
New Therapeutic Approaches for Allergy: A Review of Cell Therapy and Bio- or Nano-Material-Based Strategies
review article