2026-07-21T14:37:02Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/185192024-11-28T15:36:25Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16938col_20.500.12105_16927

00925njm 22002777a 4500 dc Paris, Juan L. author de la Torre, Paz author Flores, Ana I. author 2021-12-14 Allergy constitutes a major health issue due to its large prevalence. The established therapeutic approaches (allergen avoidance, antihistamines, and corticosteroids) do not address the underlying causes of the pathology, highlighting the need for other long-term treatment options. Antigen-specific immunotherapy enables the long-term control of allergic diseases by promoting immunological tolerance to the allergen. However, efficacious immunotherapies are not available for all possible allergens, and the risk of undesired reactions during therapy remains a concern, especially in patients with severe allergic reactions. In this context, two types of therapeutic strategies appear especially promising for the future in the context of allergy: cell therapy and bio- or nano-material-based therapy. In this review, the main strategies developed this far in these two types of strategies are discussed, with several examples illustrating the different approaches. 10.3390/pharmaceutics13122149 1999-4923 Pharmaceutics http://hdl.handle.net/10668/4125 34959429 http://hdl.handle.net/20.500.12105/18519 Allergy Cell therapy Biomaterials Nano-materials Immunotherapy Alergia e inmunología Tratamiento basado en trasplante de células y tejidos Materiales biocompatibles Nanoestructuras Inmunoterapia New Therapeutic Approaches for Allergy: A Review of Cell Therapy and Bio- or Nano-Material-Based Strategies