2026-05-22T01:55:36Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/184892024-11-28T15:17:15Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16927col_20.500.12105_16978

00925njm 22002777a 4500 dc de Miguel-Diez, Javier author Lopez-Herranz, Marta author de Miguel-Yanes, Jose M. author Perez-Farinos, Napoleon author Wärnberg, Julia author Carabantes-Alarcon, David author Jimenez-Garcia, Rodrigo author Lopez-de-Andres, Ana author 2021-10-23 Background: To describe and analyze the incidence and hospital outcomes of patients admitted with community-acquired pneumonia (CAP) according to Chronic Obstructive Pulmonary Disease (COPD) status and sex in Spanish hospitals from 2016 to 2019. Methods: We conducted a cohort study using national hospital discharge data of all patients ≥40 years with CAP. Results: A total of 500,833 patients (59.0% men) was identified. Incidence of CAP increased over time. Age adjusted incidence was 4.42-times higher in COPD patients. In-hospital mortality (IHM) was lower in men and women with COPD than in those without COPD (14.41% vs. 10.70% in men; 11.12% vs. 8.58%. in women; p < 0.001). The risk of dying in hospital increased with age, presence of several comorbidities (excluding T2DM that was a protective factor), and need for mechanical ventilation (non-invasive and invasive) during admission, irrespective of sex. Over time, the IHM decreased significantly in men and women with COPD. Men with COPD were significantly more likely to die in hospital than were COPD women (OR 1.13; 95% CI 1.07–1.21). Conclusions: Incidence of CAP was higher among subjects with COPD, although the effect of COPD was higher in men than in women. By contrast, IHM was lower in COPD patients, but men with COPD were significantly more likely to die in hospital than were COPD women. 10.3390/jcm10214889 2077-0383 Journal of Clinical Medicine http://hdl.handle.net/10668/3952 34768409 http://hdl.handle.net/20.500.12105/18489 Community-acquired pneumonia COPD Sex Incidence In-hospital mortality Neumonía Infecciones comunitarias adquiridas Enfermedad pulmonar obstructiva crónica Diferenciación sexual Incidencia Mortalidad hospitalaria Community-Acquired Pneumonia among Patients with COPD in Spain from 2016 to 2019. Cohort Study Assessing Sex Differences in the Incidence and Outcomes Using Hospital Discharge Data