2026-05-20T04:33:29Zhttps://repisalud.isciii.es/rest/oai/request
oai:repisalud.isciii.es:20.500.12105/184882024-11-28T15:00:50Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16927col_20.500.12105_16971
Repisalud author Requena-Ocaña, Nerea author Flores-Lopez, María author San Martín, Alicia author García-Marchena, Nuria author Pedraz, María author Ruiz, Juan Jesús author Serrano, Antonia author Suarez, Juan author Pavón, Francisco Javier author Rodríguez de Fonseca, Fernando author Araos, Pedro authoraffiliation [Requena-Ocaña,N; Flores-Lopez,M; García-Marchena.N; Pedraz,M; Serrano,A; Suarez,J; Pavón,FJ; Rodríguez de Fonseca,F; Araos,P] Laboratorio de Medicina Regenerativa (LMR), Unidad de Gestión Clínica de Salud Mental, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Málaga, Spain. [Requena-Ocaña,N; San Martín,A] Departamento de Psicobiología, Facultad de Psicología, Universidad Complutense de Madrid, Campus de Somosaguas, Pozuelo de Alarcón, Madrid, Spain. [García-Marchena,N] Institut D, Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP), Unidad de Adicciones-Servicio de Medicina Interna, Campus Can Ruti, Carrer del Canyet s/n, 08916 Badalona, Spain. [Ruiz,JJ] Centro Provincial de Drogodependencias (CPD) de Málaga, Diputación de Málaga, C/Ana Solo de Zaldívar, Málaga, Spain. [Suarez,J] Department of Anatomy, Legal Medicine and History of Science, School of Medicine, University of Malaga, Boulevard Louis Pasteur, Málaga, Spain. [Pavón,FJ] Instituto de Investigación Biomédica de Málaga (IBIMA), Unidad de Gestión Clínica del Corazón, Hospital Universitario Virgen de la Victoria de Málaga, Malaga, Spain. [Pavón,FJ] Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, Calle de Melchor Fernández Almagro, Madrid, Spain. [Araos,P] Departamento de Psicobiología y Metdología de las CC del Comportamiento, Facultad de Psicología, Universidad de Málaga, Málaga, Spain. 2024-02-19T15:31:47Z 2024-02-19T15:31:47Z 2021-10-22 10.1038/s41598-021-00472-7 2045-2322 Scientific Reports http://hdl.handle.net/10668/4474 34686732 http://hdl.handle.net/20.500.12105/18488 Gender significantly influences sociodemographic, medical, psychiatric and addiction variables in cocaine outpatients. Educational level may be a protective factor showing less severe addictive disorders, longer abstinence periods, and better cognitive performance. The aim was to estimate gender-based differences and the influence of educational level on the clinical variables associated with cocaine use disorder (CUD). A total of 300 cocaine-consuming patients undergoing treatments were recruited and assessed using the Psychiatric Research Interview for Substance and Mental Diseases according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision. Women developed CUD later but exhibited more consumption of anxiolytics, prevalence of anxiety disorders, eating disorders, and major depressive disorders. Alcohol and cannabis use disorders were more frequent in men. A predictive model was created and identified three psychiatric variables with good prognosis for distinguishing between women and men. Principal component analysis helped to describe the different profile types of men and women who had sought treatment. Low educational levels seemed to be a risk factor for the onset, development, and duration of CUD in both genders. Women and men exhibited different clinical characteristics that should be taken into account when designing therapeutic policies. The educational level plays a protective/risk role in the onset, development and progression of CUD, thus prolonging the years of compulsory education and implementing cognitive rehabilitation programmes could be useful. eng Alcoholism Cocaine-related disorders Anxiety disorders Major depressive disorder Outpatients Prevalence Social class Gender studies Education Spain Alcoholismo Trastornos relacionados con cocaína Trastornos de ansiedad Trastorno depresivo mayor Pacientes ambulatorios Prevalencia Clase social Estudios de género Educación España Influence of gender and education on cocaine users in an outpatient cohort in Spain research article