2026-07-21T14:14:58Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/184852024-11-28T15:24:23Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16927

00925njm 22002777a 4500 dc Pérez-Ruiz, Elisabeth author Gutiérrez, Vanesa author Muñoz, Marta author Oliver, Javier author Sánchez, Marta author Gálvez-Carvajal, Laura author Rueda-Domínguez, Antonio author Barragán, Isabel author 2021-10-15 Oral squamous cell carcinoma (OSCC) constitutes approximately 25% of all head and neck cancer, for which the consumption of tobacco and alcohol are the main associated risk factors. The field cancerization effect of OSCC is one of the main reasons for the poor survival rates associated with this disease. Despite some advances, its ccharacterization and early diagnosis continue to challenge modern oncology, and the goal of improving the prognosis remains to be achieved. Among new early diagnostic tools for OSCC that have been proposed, liquid biopsy appears to be an ideal candidate, as studies have shown that the analysis of blood and saliva provides promising data for the early detection of relapses or second tumours. 10.3390/biomedicines9101478 2227-9059 Biomedicines http://hdl.handle.net/10668/4333 34680596 http://hdl.handle.net/20.500.12105/18485 Oral cell carcinoma Field cancerization Liquid biopsy Tobacco Saliva Early diagnosis Carcinoma de células escamosas de cabeza y cuello Biopsia líquida Tabaco Diagnóstico precoz Detección precoz del cáncer Liquid Biopsy as a Tool for the Characterisation and Early Detection of the Field Cancerization Effect in Patients with Oral Cavity Carcinoma