2026-06-14T05:18:27Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/184402024-09-21T22:14:53Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16927col_20.500.12105_16989

00925njm 22002777a 4500 dc Somoza, Maria Luisa author Pérez-Sánchez, Natalia author Victorio-Puche, Laura author Martín-Pedraza, Laura author Esteban Rodríguez, Angel author Blanca-López, Natalia author Abel Fernández González, Eva author Ruano-Zaragoza, María author Prieto-Moreno Pfeifer, Ana author Fernández Caldas, Enrique author Morán Morales, Miriam author Fernández Sánchez, Francisco Javier author López Sánchez, José Damián author Jiménez Rodríguez, Teodorikez Wilfox author Subiza Garrido-Lestache, José Luis author Canto Díez, Gabriela author Blanca Gómez, Miguel author Cornejo-García, José Antonio author 2021-08-19 Peach tree allergens are present in fruit, pollen, branches, and leaves, and can induce systemic, respiratory, cutaneous, and gastrointestinal symptoms. We studied the capacity of peach fruit/Pru p 1, Pru p 3, Pru p 4, Pru p 7 and peach pollen/Pru p 9 for inducing symptoms following oral or respiratory exposure in a large group of subjects. We included 716 adults (aged 21 to 83 y.o.) exposed to peach tree pollen and fruit intake in the study population. Participants completed a questionnaire and were skin tested with a panel of inhalant and food allergens, including peach tree pollen, Pru p 9 and peach fruit skin extract. Immunoglobulin E antibodies (SIgE) to Pru p 1, Pru p 3, Pru p 4 and Pru p 7 were quantified. Sensitised subjects underwent oral food challenge with peach fruit and nasal provocation test with peach tree pollen and Pru p 9. The prevalence of sensitisation to peach fruit was 5% and most of these had SIgE to Pru p 3, with a very low proportion to Pru p 4 SIgE and no SIgE to Pru p 1 and Pru p 7. In only 1.8%, anaphylaxis was the clinical entity induced. Cases with positive skin tests to peach and SIgE to Pru p 3 presented a good tolerance after oral challenge with peach fruit. The prevalence of skin sensitisation to peach tree pollen was 22%, with almost half recognising Pru p 9. This induced respiratory symptoms in those evaluated by nasal provocation. In a large population group exposed to peach fruit and peach tree pollen, most individuals were tolerant, even in those with SIgE to Pru p 3. A positive response to Pru p 9 was associated with respiratory allergy. 10.1371/journal.pone.0255305 1932-6203 PloS one http://hdl.handle.net/10668/18393 34411133 http://hdl.handle.net/20.500.12105/18440 Subjects develop tolerance to Pru p 3 but respiratory allergy to Pru p 9: A large study group from a peach exposed population.