2026-06-14T03:32:33Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/183222024-02-19T15:27:58Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16927col_20.500.12105_16959
Repisalud
author
Rodríguez-Capitán, Jorge
author
Sánchez-Pérez, Andrés
author
Ballesteros-Pradas, Sara
author
Millán-Gómez, Mercedes
author
Cardenal-Piris, Rosa
author
Oneto-Fernández, Manuel
author
Gutiérrez-Alonso, Lola
author
Rivera-López, Ricardo
author
Guisado-Rasco, Agustín
author
Cano-García, Macarena
author
Gutiérrez-Bedmar, Mario
author
Jiménez-Navarro, Manuel
2024-02-19T15:27:58Z
2024-02-19T15:27:58Z
2021-04-25
10.3390/jcm10091863
2077-0383
Journal of clinical medicine
http://hdl.handle.net/10668/17704
33923110
http://hdl.handle.net/20.500.12105/18322
The clinical significance of non-obstructive coronary artery disease is the subject of debate. Our objective was to evaluate the long-term cardiovascular prognosis associated with non-obstructive coronary artery disease in patients undergoing coronary angiography, and to conduct a stratification by sex, diabetes, and clinical indication. We designed a multi-centre retrospective longitudinal observational study of 3265 patients that were classified into three groups: normal coronary arteries (lesion 70%, 1196 patients). During a mean follow-up of 43 months, we evaluated a combined cardiovascular event: acute myocardial infarction, stroke, hospitalization for heart failure, or cardiovascular death. Multivariable-adjusted Cox proportional hazard models showed a worse prognosis in patients with non-obstructive coronary artery disease, in comparison with patients of normal coronary arteries group, in the total population (hazard ratio 1.72, 95% confidence interval 1.23-2.39; p for trend
eng
acute coronary syndrome
coronary angiography
coronary artery disease
diabetes mellitus
sex
Prognostic Implication of Non-Obstructive Coronary Lesions: A New Classification in Different Settings.
research article