2026-05-21T23:19:51Zhttps://repisalud.isciii.es/rest/oai/request
oai:repisalud.isciii.es:20.500.12105/182962024-09-21T20:46:31Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16927col_20.500.12105_16985
Repisalud author Roibal Pravio, Javier author Barge Caballero, Eduardo author Barbeito Caamaño, Cayetana author Paniagua Martin, Maria Jesus author Barge Caballero, Gonzalo author Couto Mallon, David author Pardo Martinez, Patricia author Grille Cancela, Zulaika author Blanco Canosa, Paula author García Pinilla, Jose Manuel author Vázquez Rodríguez, Jose Manuel author Crespo Leiro, Maria Generosa 2024-02-19T15:26:39Z 2024-02-19T15:26:39Z 2021-03-27 10.1002/ehf2.13275 2055-5822 ESC heart failure http://hdl.handle.net/10668/17411 33773098 http://hdl.handle.net/20.500.12105/18296 Maximum oxygen uptake (VO2max ) is an essential parameter to assess functional capacity of patients with heart failure (HF). We aimed to identify clinical factors that determine its value, as they have not been well characterized yet. We conducted a retrospective, observational, single-centre study of 362 consecutive patients with HF who underwent cardiopulmonary exercise testing (CPET) as part of standard clinical assessment since 2009-2019. CPET was performed on treadmill, according to Bruce's protocol (n = 360) or Naughton's protocol (n = 2). We performed multivariable linear regression analyses in order to identify independent clinical predictors associated with peak VO2max . Mean age of study patients was 57.3 ± 10.9 years, mean left ventricular ejection fraction was 32.8 ± 14.2%, and mean VO2max was 19.8 ± 5.2 mL/kg/min. Eighty-nine (24.6%) patients were women, and 114 (31.5%) had ischaemic heart disease. Multivariable linear regression analysis identified six independent clinical predictors of VO2max , including NYHA class (B coefficient = -2.585; P  The severity of HF (NYHA class, NT-proBNP) as well as age, body composition and haemoglobin levels influence significantly exercise capacity. In patients with HF, the right ventricular systolic function is of greater importance for the physical capacity than the left ventricular systolic function. eng Cardiopulmonary exercise testing Heart failure Maximum oxygen uptake Prognostic value Determinants of maximal oxygen uptake in patients with heart failure. research article