2026-04-27T07:47:16Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/182292024-11-28T15:08:25Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16927
Repisalud
author
Moreno-Küstner, Berta
author
Guzman-Parra, Jose
author
Pardo, Yolanda
author
Sanchidrián, Yolanda
author
Díaz-Ruiz, Sebastián
author
Mayoral-Cleries, Fermin
authoraffiliation
[Moreno-Küstner,B; Sanchidrián,Y] Departamento de Personalidad, Evaluación y Tratamiento Psicológico, Grupo GAP, Facultad de Psicología, Universidad de Málaga, Spain. [Guzman-Parra,J; Pardo,Y; Mayoral-Cleries,F] Department of Mental Health, University General Hospital of Malaga. Biomedical Research Institute of Malaga (IBIMA), Spain. [Díaz-Ruiz,S] Instituto de Medicina Legal de Málaga, Spain.
2024-02-19T15:24:40Z
2024-02-19T15:24:40Z
2021
2045-7960
http://hdl.handle.net/10668/4210
http://hdl.handle.net/20.500.12105/18229
33536113
10.1017/S2045796020001146
2045-7979
Epidemiology and Psychiatric Sciences
Aims: There is evidence that patients with schizophrenia spectrum disorders present higher mortality in comparison with the general population. The aim of this study was to analyse the causes of mortality and sociodemographic factors associated with mortality, standardised mortality ratios (SMRs), life expectancy and potential years of life lost (YLL) in patients with schizophrenia spectrum disorders in Spain. Methods: The study included a cohort of patients from the Malaga Schizophrenia Case Register (1418 patients; 907 males; average age 42.31 years) who were followed up for a minimum of 10 years (median = 13.43). The factors associated with mortality were analysed with a survival analysis using Cox's proportional hazards regression model. Results: The main causes of mortality in the cohort were circulatory disease (21.45%), cancer (17.09%) and suicide (13.09%). The SMR of the cohort was more than threefold that of the population of Malaga (3.19). The life expectancy at birth was 67.11 years old, which is more than 13 years shorter than that of the population of Malaga. The YLL was 20.74. The variables associated with a higher risk of mortality were age [adjusted hazard ratio (AHR) = 1.069, p < 0.001], male gender (AHR = 1.751, p < 0.001) and type of area of residence (p = 0.028; deprived urban zone v. non-deprived urban area, AHR = 1.460, p = 0.028). In addition, receiving welfare benefit status in comparison with employed status (AHR = 1.940, p = 0.008) was associated with increased mortality. Conclusions: There is excess mortality in patients with schizophrenia spectrum disorders and also an association with age, gender, socioeconomic inequalities and receiving welfare benefits. Efforts directed towards improved living conditions could have a positive effect on reducing mortality.
eng
Health outcomes
Psychosis
Risk factors
Schizophrenia
Suicide
Evaluación de resultado en la atención de salud
Trastornos psicóticos
Factores de riesgo
Esquizofrenia
Suicidio
Excess mortality in patients with schizophrenia spectrum disorders in Malaga (Spain): A cohort study
research article