2026-04-29T06:15:53Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/180832025-04-23T08:01:09Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16927

00925njm 22002777a 4500 dc Raigon Ponferrada, Aida author Guerrero Orriach, Jose Luis author Malo Manso, Alfredo author Sepúlveda-Haro, Enrique author Romero Molina, Salvador author Fontaneda Heredia, Ana author Baena Lopez, Manolo author Cruz Mañas, Jose author 2020-07-27 Cancer remains a primary cause of morbidity and mortality worldwide, and its incidence continues to increase. The most common cause of death in cancer patients is tumour recurrence. Surgery is the gold standard in the treatment of most tumours. However, cancer surgery can lead to the release of tumour cells into the systemic circulation. Surgical stress and several perioperative factors have been suggested to boost tumour growth, thereby increasing the risk of metastatic recurrence. Preclinical and clinical studies suggest that anaesthetics and adjuvants administered during the perioperative period may impact cancer recurrence and survival. This document summarises the current evidence regarding the effects of anaesthetic drugs and analgesic techniques on the immune system, systemic inflammatory response and tumour cells, as well as their impact on cancer recurrence. http://hdl.handle.net/10668/3969 http://hdl.handle.net/20.500.12105/18083 32863874 10.3332/ecancer.2020.1080 1754-6605 Ecancermedicalscience Anaesthesia Analgesia Cancer recurrence Metastases Anaesthetics Regional anaesthesia Opioid NSAIDs Anestesia en procedimientos quirúrgicos cardíacos Metástasis de la neoplasia Analgésicos opioides Antiinflamatorios no esteroideos Anaesthesia and cancer: can anaesthetic drugs modify gene expression?