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Repisalud author Marcos-Delgado, Alba author Fernández-Villa, Tania author Martínez-González, Miguel Ángel author Salas-Salvadó, Jordi author Corella, Dolores author Castañer, Olga author Martínez, J. Alfredo author Alonso-Gómez, Ángel M. author Wärnberg, Julia author Vioque, Jesús author Romaguera, Dora author López-Miranda, José author Estruch, Ramon author Tinahones, Francisco J. author Lapetra, José author Serra-Majem, J. LLuís author García-Molina, Laura author Tur, Josep A. author de Paz, José Antonio author Pintó, Xavier author Delgado-Rodríguez, Miguel author Matía-Martín, Pilar author Vidal, Josep author Vázquez, Clotilde author Daimiel, Lidia author Ros, Emilio author Babio, Nancy author Gimenez-Alba, Ignacio M. author Toledo, Estefanía author Zomeño, María Dolores author Zulet, M. A. author Vaquero-Luna, Jessica author Pérez-López, Jessica author Pastor-Morel, Ana author Galmes-Panades, Aina M. author García-Rios, Antonio author Casas, Rosa author Bernal-López, María Rosa author Santos-Lozano, José Manuel author Becerra-Tomás, Nerea author Ortega-Azorin, Carolina author Vázquez-Ruiz, Zenaida author Pérez-Vega, Karla Alejandra author Abete, Itziar author Sorto-Sánchez, Carolina author Palau-Galindo, Antoni author Galilea-Zabalza, Iñigo author Muñoz-Martínez, Júlia author Martín, Vicente authoraffiliation [Marcos-Delgado,A; Fernández-Villa,T; de Paz,A; Martín,V] Institute of Biomedicine (IBIOMED), University of León, León, Spain. [Martínez-González,MÁ; Salas-Salvadó,J; Corella,D; Castañer,O; Martínez,JA; Alonso-Gómez,ÁM; Wärnberg,J; Romaguera,D; López-Miranda,J; Estruch,R; Tinahones,FJ; Lapetra,J; Serra-Majem,JL; Tur,JA; Pintó,X; Vázquez,C; Ros,E; Babio,N; Gimenez-Alba,IM; Toledo,E; Pérez-López,J; Galmes-Panades,AM; García-Rios,A; Casas,R; Bernal-López,MR; Santos-Lozano,JM; Becerra-Tomás,N; Ortega-Azorín,C; Vázquez-Ruiz,Z; Palau-Galindo,A; Galilea-Zabala,I] Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición. [Martínez-González,MÁ; Toledo,E; Vázquez-Ruiz,Z] Department of Preventive Medicine and Public Health, IdiSNA, University of Navarra, Pamplona, Spain. [Martínez-González,MÁ] Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA. [Salas-Salvadó,J; Babio,N; Becerra-Tomás,N; Palau-Galindo,A] Departament de Bioquímica i Biotecnologia, Unitat de Nutrició, Universitat Rovira i Virgili, Reus, Spain. [Salas-Salvadó,J] Nutrition Unit, University Hospital of Sant Joan de Reus, Reus, Spain. [Salas-Salvadó,J; Babio,N; Becerra-Tomás,N; Palau-Galindo,A] Institut d’Investigació Sanitària Pere Virgili (IISPV), Reus, Spain. [Corella,D; Gimenez-Alba,IM; Becerra-Tomás,N; Ortega-Azorin,C] Department of Preventive Medicine, University of Valencia, Valencia, Spain. [Castañer,O; Zomeño,MD; Pérez-Vega,KA; Muñoz-Martínez,J] Unit of Cardiovascular Risk and Nutrition, Institut Hospital del Mar de Investigaciones Médicas Municipal d’Investigació Médica (IMIM), Barcelona, Spain. [Martínez,JA; Zulet,MA; Abete,I] Department of Nutrition, Food Sciences, and Physiology, Center for Nutrition Research, University of Navarra, Pamplona, Spain. [Martínez,JA] Precision Nutrition and Cardiometabolic Health Program, IMDEA Food, CEI UAM + CSIC, Madrid, Spain. [Alonso-Gómez,ÁM; Vaquero-Luna,J; Sorto-Sánchez,C] Bioaraba Health Research Institute, Cardiovascular, Respiratory and Metabolic Area, Osakidetza Basque Health Service, Araba University Hospital, University of the Basque Country UPV/EHU, Vitoria-Gasteiz, Spain. [Wärnberg,J; Pérez-López,J] Department of Nursing, Institute of Biomedical Research in Malaga (IBIMA), University of Málaga, Málaga, Spain. [Vioque,J; García-Molina,L; Martín,V] CIBER de Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain. [Vioque,J] Instituto de Investigación Sanitaria y Biomédica de Alicante, ISABIAL, Alicante, Spain. [Romaguera,D; Galmes-Panades,AM] Health Research Institute of the Balearic Islands (IdISBa), University Hospital Son Espases, Palma de Mallorca, Spain. [López-Miranda,J; García-Rios,A] Department of Internal Medicine, Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, Cordoba, Spain. [Estruch,R; Casas,R] Department of Internal Medicine, Institut d’Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Hospital Clinic, University of Barcelona, Barcelona, Spain. [Tinahones,FJ] Virgen de la Victoria Hospital, Department of Endocrinology, Instituto de Investigación Biomédica de Málaga (IBIMA), University of Málaga,Málaga, Spain. [Lapetra,J; Santos-Lozano,JM] Department of Family Medicine, Research Unit, Distrito Sanitario Atención Primaria Sevilla, Sevilla, Spain. [Serra-Majem,JL] Research Institute of Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria & Centro Hospitalario Universitario Insular Materno Infantil (CHUIMI), Canarian Health Service, Las Palmas de Gran Canaria, Spain. [García-Molina,L] Department of Preventive Medicine and Public Health, University of Granada, Granada, Spain. [Tur,JA] Research Group on Community Nutrition & Oxidative Stress, University of Balearic Islands, Palma de Mallorca, Spain. [Pintó,X] Lipids and Vascular Risk Unit, Internal Medicine, Hospital Universitario de Bellvitge, Hospitalet de Llobregat, Barcelona, Spain. [Delgado-Rodríguez,M] Nutritional Genomics and Epigenomics Group, IMDEA Food, CEI UAM + CSIC, 28049 Madrid, Spain. [Delgado-Rodríguez,M] Division of Preventive Medicine, Faculty of Medicine, University of Jaén, Jaén, Spain. [Matía-Martín,P] Department of Endocrinology and Nutrition, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdISSC), Madrid, Spain. [Vidal,J] CIBER Diabetes y Enfermedades Metabólicas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Madrid, Spain. [Vidal,J] Department of Endocrinology, Institut d’Investigacions Biomédiques August Pi Sunyer (IDIBAPS), Hospital Clinic, University of Barcelona, Barcelona, Spain. [Vázquez,C] Department of Endocrinology and Nutrition, Hospital Fundación Jimenez Díaz, Instituto de Investigaciones Biomédicas IISFJD, University Autonoma, Madrid, Spain. [Daimiel,L] Nutritional Control of the Epigenome Group, Precision Nutrition and Obesity Program, IMDEA Food, CEI UAM + CSIC, Madrid, Spain. [Ros,E] Lipid Clinic, Department of Endocrinology and Nutrition, Institut d’Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Hospital Clínic, Barcelona, Spain. [Pastor-Morel,A] Centro de Salud Cabo Huertas, Alicante, Spain. [Bernal-López.MR] Departament of Internal Medicine, Regional University Hospital of Malaga, Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, Spain. 2024-02-12T19:46:21Z 2024-02-12T19:46:21Z 2020-05-25 10.3390/ijerph17103728 1660-4601 1661-7827 International Journal of Environmental Research and Public Health http://hdl.handle.net/10668/4368http://hdl.handle.net/20.500.13003/10764 32466190 L2004441273 2-s2.0-85085635429 http://hdl.handle.net/20.500.12105/18057 539300900385 The main objective of this study was to examine the relationship between the level of physical activity (PA) and the degree of obesity with health-related quality of life (HRQoL) in individuals with metabolic syndrome (MetS) who participated in the Predimed-Plus study. A total of 6875 subjects between 55 and 75 years of age with MetS were selected and randomized in 23 Spanish centers. Subjects were classified according to categories of body mass index (BMI). PA was measured with the validated Registre Gironí del Cor (REGICOR) questionnaire and subjects were classified according to their PA level (light, moderate, vigorous) and the HRQoL was measured with the validated short-form 36 (SF-36) questionnaire. By using the ANOVA model, we found a positive and statistically significant association between the level of PA and the HRQoL (aggregated physical and mental dimensions p < 0.001), but a negative association with higher BMI in aggregated physical dimensions p < 0.001. Furthermore, women obtained lower scores compared with men, more five points in all fields of SF-36. Therefore, it is essential to promote PA and body weight control from primary care consultations to improve HRQoL, paying special attention to the differences that sex incurs. eng Health-related quality of life Physical activity Obesity Body mass index Metabolic syndrome Calidad de vida Ejercicio físico Obesidad Índice de masa corporal Síndrome metabólico The Effect of Physical Activity and High Body Mass Index on Health-Related Quality of Life in Individuals with Metabolic Syndrome research article