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oai:repisalud.isciii.es:20.500.12105/178842024-09-21T22:40:33Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16927col_20.500.12105_16961col_20.500.12105_16967col_20.500.12105_16968col_20.500.12105_16969col_20.500.12105_16982col_20.500.12105_16983col_20.500.12105_16989
Repisalud author Julibert, Alicia author Bibiloni, Maria Del Mar author Bouzas, Cristina author Martínez-González, Miguel Ángel author Salas-Salvadó, Jordi author Corella, Dolores author Zomeño, Maria Dolors author Romaguera, Dora author Vioque, Jesús author Alonso-Gómez, Ángel M author Wärnberg, Julia author Martínez, J Alfredo author Serra-Majem, Luís author Estruch, Ramon author Tinahones, Francisco J author Lapetra, José author Pintó, Xavier author Lopez-Miranda, José author García-Molina, Laura author Gaforio, José Juan author Matía-Martín, Pilar author Daimiel, Lidia author Martín-Sánchez, Vicente author Vidal, Josep author Vázquez, Clotilde author Ros, Emili author Toledo, Estefanía author Becerra-Tomás, Nerea author Pórtoles, Olga author Pérez-Vega, Karla A author Fiol, Miquel author Torres-Collado, Laura author Tojal-Sierra, Lucas author Carabaño-Moral, Rosa author Abete, Itziar author Sanchez-Villegas, Almudena author Casas, Rosa author Bernal-López, María Rosa author Santos-Lozano, José Manuel author Galera, Ana author Ugarriza, Lucía author Ruiz-Canela, Miguel author Babio, Nancy author Coltell, Oscar author Schröder, Helmut author Konieczna, Jadwiga author Orozco-Beltrán, Domingo author Sorto-Sánchez, Carolina author Eguaras, Sonia author Barrubés, Laura author Fitó, Montserrat author Tur, Josep A author Predimed-Plus Investigators 2024-02-10T20:01:46Z 2024-02-10T20:01:46Z 2019-06-29 10.3390/nu11071493 2072-6643 Nutrients http://hdl.handle.net/10668/14204http://hdl.handle.net/20.500.13003/16097 31261967 L2002354203 2-s2.0-85069267692 http://hdl.handle.net/20.500.12105/17884 478885400086 Background: The effect of dietary fat intake on the metabolic syndrome (MetS) and in turn on cardiovascular disease (CVD) remains unclear in individuals at high CVD risk. Objective: To assess the association between fat intake and MetS components in an adult Mediterranean population at high CVD risk. Design: Baseline assessment of nutritional adequacy in participants (n = 6560, men and women, 55-75 years old, with overweight/obesity and MetS) in the PREvención con DIeta MEDiterránea (PREDIMED)-Plus randomized trial. Methods: Assessment of fat intake (total fat, monounsatured fatty acids: MUFA, polyunsaturated fatty acids: PUFA, saturated fatty acids: SFA, trans-fatty acids: trans-FA, linoleic acid, α-linolenic acid, and ω-3 FA) using a validated food frequency questionnaire, and diet quality using 17-item Mediterranean dietary questionnaire and fat quality index (FQI). Results: Participants in the highest quintile of total dietary fat intake showed lower intake of energy, carbohydrates, protein and fiber, but higher intake of PUFA, MUFA, SFA, TFA, LA, ALA and ω-3 FA. Differences in MetS components were found according to fat intake. Odds (5th vs. 1st quintile): hyperglycemia: 1.3-1.6 times higher for total fat, MUFA, SFA and ω-3 FA intake; low high-density lipoprotein cholesterol (HDL-c): 1.2 higher for LA; hypertriglyceridemia: 0.7 lower for SFA and ω-3 FA intake. Conclusions: Dietary fats played different role on MetS components of high CVD risk patients. Dietary fat intake was associated with higher risk of hyperglycemia. eng Mediterranean diet Cardiovascular disease risk Dietary fat Fat intake Fatty acids Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk research article