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00925njm 22002777a 4500 dc Papandreou, Christopher author Babio, Nancy author Díaz-López, Andrés author Martínez-González, Miguel Á author Becerra-Tomas, Nerea author Corella, Dolores author Schröder, Helmut author Romaguera, Dora author Vioque, Jesús author Alonso-Gómez, Ángel M author Wärnberg, Julia author Martínez, Alfredo J author Serra-Majem, Lluís author Estruch, Ramon author Muñoz-Garach, Araceli author Lapetra, José author Pintó, Xavier author Tur, Josep A author Garcia-Rios, Antonio author Bueno-Cavanillas, Aurora author Delgado-Rodríguez, Miguel author Matía-Martín, Pilar author Daimiel, Lidia author M Sánchez, Vicente author Vidal, Josep author Vázquez, Clotilde author Ros, Emilio author Ruiz-Canela, Miguel author Bulló, Mónica author Sorli, Jose V author Quifer, Mireia author Colom, Antoni author Oncina-Canovas, Alejandro author T Sierra, Lucas author Barón-López, Javier author Pérez-Farinós, Napoleón author Abete, Itziar author Sanchez-Villegas, Almudena author Casas, Rosa author F García, José C author Santos-Lozano, José M author Corbella, Emili author Del M Bibiloni, Maria author Diez-Espino, Javier author Asensio, Eva M author Torras, Laura author Morey, Marga author Compañ-Gabucio, Laura author S Lete, Itziar author Cenoz-Osinaga, Juan Carlos author Castañer, Olga author Salas-Salvadó, Jordi author 2019-04-01 The aim of the study was to evaluate sleep duration and sleep variability in relation to serum uric acid (SUA) concentrations and SUA to creatinine ratio. This is a cross-sectional analysis of baseline data from 1842 elderly participants with overweight/obesity and metabolic syndromein the (Prevención con Dieta Mediterránea) PREDIMED-Plus trial. Accelerometry-derived sleep duration and sleep variability were measured. Linear regression models were fitted to examine the aforementioned associations. A 1 hour/night increment in sleep duration was inversely associated with SUA concentrations (β = 0.07, p = 0.047). Further adjustment for leukocytes attenuated this association (p = 0.050). Each 1-hour increment in sleep duration was inversely associated with SUA to creatinine ratio (β = 0.15, p = 0.001). The findings of this study suggest that longer sleep duration is associated with lower SUA concentrations and lower SUA to creatinine ratio. 10.3390/nu11040761 2072-6643 Nutrients http://hdl.handle.net/10668/13784 http://hdl.handle.net/20.500.13003/17550 30939748 L2001900059 2-s2.0-85064224623 http://hdl.handle.net/20.500.12105/17839 467749800054 Actigraphy Serum uric acid Serum uric acid to creatinine ratio Sleep duration Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk