2026-06-14T03:32:31Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/178372024-02-10T20:01:03Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16927

00925njm 22002777a 4500 dc García-Aranda, Marilina author Redondo, Maximino author 2019-03-27 Colorectal cancer is the third most common malignancy in men and the second most common cancer in women. Despite the success of screening programs and the development of adjuvant therapies, the global burden of colorectal cancer is expected to increase by 60% to more than 2.2 million new cases and 1.1 million deaths by 2030. In recent years, a great effort has been made to demonstrate the utility of protein kinase inhibitors for cancer treatment. Considering this heterogeneous disease is defined by mutations that activate different Receptor Tyrosine Kinases (RTKs) and affect downstream components of RTK-activated transduction pathways, in this review we analyze the potential utility of different kinase inhibitors for colorectal cancer treatment. 10.3390/cancers11040433 2072-6694 Cancers http://hdl.handle.net/10668/13778 30934752 http://hdl.handle.net/20.500.12105/17837 Cancer Colorectal Kinases Receptor Target Targeting Receptor Kinases in Colorectal Cancer.