2026-07-23T19:37:08Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/176952025-01-13T12:49:10Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609col_20.500.12105_25179
Repisalud
author
Ruiz-López, María José
author
Aguilera-Sepúlveda, Pilar
author
Cebrián-Camisón, Sonia
author
Figuerola, Jordi
author
Magallanes, Sergio
author
Varona Fernandez, Sarai
author
Cuesta de la Plaza, Isabel
author
Cano-Gómez, Cristina
author
Sánchez-Mora, Patricia
author
Camacho, Juan
author
Sánchez-Peña, Carolina
author
Marchena, Francisco José
author
Ameyugo, Ulises
author
Ruíz, Santiago
author
Sánchez-Seco, María Paz
author
Agüero, Montserrat
author
Jiménez-Clavero, Miguel Ángel
author
Fernández-Pinero, Jovita
author
Vazquez, Ana
funder
Regional Government of Andalusia (España)
funder
Agencia Estatal de Investigación (España)
funder
Instituto de Salud Carlos III
funder
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (España)
funder
Unión Europea. Comisión Europea. NextGenerationEU
2024-02-09T11:54:23Z
2024-02-09T11:54:23Z
2023-12-01
Viruses. 2023 Dec 1;15(12):2372.
10.3390/v15122372
1999-4915
Viruses
38140614
http://hdl.handle.net/20.500.12105/17695
West Nile Virus (WNV) is a mosquito vector-borne zoonosis with an increasing incidence in Europe that has become a public health concern. In Spain, although local circulation has been known for decades, until 2020, when a large outbreak occurred, West Nile Virus cases were scarce and mostly occurred in southern Spain. Since then, there have been new cases every year and the pathogen has spread to new regions. Thus, monitoring of circulating variants and lineages plays a fundamental role in understanding WNV evolution, spread and dynamics. In this study, we sequenced WNV consensus genomes from mosquito pools captured in 2022 as part of a newly implemented surveillance program in southern Spain and compared it to other European, African and Spanish sequences. Characterization of WNV genomes in mosquitoes captured in 2022 reveals the co-circulation of two WNV lineage 1 variants, the one that caused the outbreak in 2020 and another variant that is closely related to variants reported in Spain in 2012, France in 2015, Italy in 2021-2022 and Senegal in 2012-2018. The geographic distribution of these variants indicates that WNV L1 dynamics in southern Europe include an alternating dominance of variants in some territories.
eng
Culex
Flavivirus
Genetic variants
Spain
Vector-borne diseases
WNV lineage 1
Zoonosis
Re-Emergence of a West Nile Virus (WNV) Variant in South Spain with Rapid Spread Capacity
research article
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URL
https://repisalud.isciii.es/bitstreams/02553bbc-b8a0-49e9-b484-20a2d124e170/download
File
MD5
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application/pdf
Re-EmergenceWestNileVirus_2024.pdf
URL
https://repisalud.isciii.es/bitstreams/2a8be9b1-f0b5-4361-9f2f-be2379ff19f9/download
File
MD5
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text/plain
Re-EmergenceWestNileVirus_2024.pdf.txt