2026-04-29T12:23:37Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/176712024-11-29T15:59:44Zcom_20.500.12105_2173com_20.500.12105_2051col_20.500.12105_19597
Repisalud
author
Grazioso, Tatiana P
author
Djouder, Nabil
funder
Asociación Española Contra el Cáncer
funder
Ministerio de Ciencia (España)
funder
Instituto de Salud Carlos III
2024-02-08T21:24:06Z
2024-02-08T21:24:06Z
2023-07-21
iScience . 2023 ;26(7):107010.
10.1016/j.isci.2023.107010
2589-0042
iScience
37332670
http://hdl.handle.net/20.500.12105/17671
Cold therapy has been used for centuries, from Julius Caesar to Mohandas Gandhi, as a potent therapeutic approach. However, it has been largely forgotten in modern medicine. This review explores the history of cold therapy and its potential application as a therapeutic strategy against various diseases, including cancer. We examine the different techniques of cold exposure and the use of other therapeutical approaches, such as cryoablation, cryotherapy, cryoimmunotherapy, cryothalectomy, and delivery of cryogen agents. While clinical trials using cold therapy for cancer treatment are still limited, recent research shows promising results in experimental animal cancer models. This area of research is becoming increasingly significant and warrants further investigation.
eng
The forgotten art of cold therapeutic properties in cancer: A comprehensive historical guide.
journal article
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URL
https://repisalud.isciii.es/bitstreams/e4c7c99f-0a17-46e1-add0-d1b1454ae793/download
File
MD5
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application/pdf
Theforgottenartofcold_2023.pdf
URL
https://repisalud.isciii.es/bitstreams/768148bb-6c2f-4696-8bb7-1c8fa3118ca4/download
File
MD5
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text/plain
Theforgottenartofcold_2023.pdf.txt