2026-06-14T03:51:49Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/176482024-11-28T15:16:50Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16927col_20.500.12105_16961col_20.500.12105_16967col_20.500.12105_16968col_20.500.12105_16969col_20.500.12105_16982col_20.500.12105_16983col_20.500.12105_16989

00925njm 22002777a 4500 dc Sánchez-Villegas, Almudena author Álvarez-Pérez, Jacqueline author Toledo, Estefanía author Salas-Salvadó, Jordi author Ortega-Azorín, Carolina author Zomeño, Maria Dolores author Vioque, Jesús author Martínez, Jose Alfredo author Romaguera, Dora author Pérez-López, Jessica author López-Miranda, José author Estruch, Ramón author Bueno-Cavanillas, Aurora author Arós, Fernando author Tur, Josep A author Tinahones, Francisco J author Lecea, Oscar author Martín, Vicente author Ortega-Calvo, M author Vázquez, Clotilde author Pintó, Xavier author Vidal, Josep author Daimiel, Lidia author Delgado-Rodríguez, Miguel author Matía, Pilar author Corella, Dolores author Díaz-López, Andrés author Babio, Nancy author Muñoz, Miguel Ángel author Fitó, Montserrat author García de la Hera, Manoli author Abete, Itziar author García-Rios, Antonio author Ros, Emilio author Ruíz-Canela, Miguel author Martínez-González, Miguel Ángel author Izquierdo, Marisol author Serra-Majem, Lluis author 2018-12-18 Background: The aim of this analysis was to ascertain the type of relationship between fish and seafood consumption, omega-3 polyunsaturated fatty acids (-3 PUFA) intake, and depression prevalence. Methods: Cross-sectional analyses of the PREDIMED-Plus trial. Fish and seafood consumption and -3 PUFA intake were assessed through a validated food-frequency questionnaire. Self-reported life-time medical diagnosis of depression or use of antidepressants was considered as outcome. Depressive symptoms were collected by the Beck Depression Inventory-II. Logistic regression models were used to estimate the association between seafood products and -3 PUFA consumption and depression. Multiple linear regression models were fitted to assess the association between fish and long-chain (LC) -3 PUFA intake and depressive symptoms. Results: Out of 6587 participants, there were 1367 cases of depression. Total seafood consumption was not associated with depression. The odds ratios (ORs) (95% confidence intervals (CIs)) for the 2nd, 3rd, and 4th quintiles of consumption of fatty fish were 0.77 (0.63-0.94), 0.71 (0.58-0.87), and 0.78 (0.64-0.96), respectively, and p for trend = 0.759. Moderate intake of total LC -3 PUFA (approximately 0.5-1 g/day) was significantly associated with a lower prevalence of depression. Conclusion: In our study, moderate fish and LC -3 PUFA intake, but not high intake, was associated with lower odds of depression suggesting a U-shaped relationship. 10.3390/nu10122000 2072-6643 Nutrients http://hdl.handle.net/10668/13332 http://hdl.handle.net/20.500.13003/8986 30567286 L625530871 2-s2.0-85058901912 http://hdl.handle.net/20.500.12105/17648 455073200181 Depression Docosahexaenoic acid Eicosapentaenoic acid Fish Omega-3 Seafood Consumption, Omega-3 Fatty Acids Intake, and Life-Time Prevalence of Depression in the PREDIMED-Plus Trial.