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00925njm 22002777a 4500 dc Mallorquí-Bagué, Núria author Lozano-Madrid, María author Toledo, Estefanía author Corella, Dolores author Salas-Salvadó, Jordi author Cuenca-Royo, Aida author Vioque, Jesús author Romaguera, Dora author Martínez, J Alfredo author Wärnberg, Julia author López-Miranda, José author Estruch, Ramón author Bueno-Cavanillas, Aurora author Alonso-Gómez, Ángel author Tur, Josep A author Tinahones, Francisco J author Serra-Majem, Lluís author Martín, Vicente author Lapetra, José author Vázquez, Clotilde author Pintó, Xavier author Vidal, Josep author Daimiel, Lidia author Gaforio, José J author Matía, Pilar author Ros, Emilio author Granero, Roser author Buil-Cosiales, Pilar author Barragán, Rocío author Bulló, Mònica author Castañer, Olga author García-de-la-Hera, Manoli author Yáñez, Aina M author Abete, Itziar author García-Ríos, Antonio author Ruiz-Canela, Miguel author Díaz-López, Andrés author Jiménez-Murcia, Susana author Martínez-González, Miguel A author De la Torre, Rafael author Fernández-Aranda, Fernando author 2018-10-31 This study cross-sectionally examines in the elderly population: (a) the association of type 2 diabetes with executive function (EF); (b) the effect of BMI on both type 2 diabetes and EF; (c) the association between glycaemia control and EF in type 2 diabetes. 6823 older individuals with overweight/obesity and metabolic syndrome participating in the PREDIMED-PLUS study, were assessed with a battery of cognitive tests and a medical interview. ANOVA showed a significantly worse performance on EF in type 2 diabetes vs. non-diabetic individuals. Two complementary models were displayed: (1) in the whole sample, the presence of type 2 diabetes, depressive symptoms and BMI had a direct negative effect on EF, while apnoea had an indirect negative effect; (2) in the diabetes subsample, higher illness duration was associated with worse performance in EF. Participants with type 2 diabetes and HbA1c 10.1038/s41598-018-33843-8 2045-2322 Scientific reports http://hdl.handle.net/10668/13146 http://hdl.handle.net/20.500.13003/9064 30382190 L624724993 2-s2.0-85055818232 http://hdl.handle.net/20.500.12105/17637 448814600026 Type 2 diabetes and cognitive impairment in an older population with overweight or obesity and metabolic syndrome: baseline cross-sectional analysis of the PREDIMED-plus study.