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00925njm 22002777a 4500 dc Peinado, Héctor author Olmeda, David author Cano, Amparo author 2007-06 The molecular mechanisms that underlie tumour progression are still poorly understood, but recently our knowledge of particular aspects of some of these processes has increased. Specifically, the identification of Snail, ZEB and some basic helix-loop-helix (bHLH) factors as inducers of epithelial-mesenchymal transition (EMT) and potent repressors of E-cadherin expression has opened new avenues of research with potential clinical implications. Nat Rev Cancer. 2007;7(6):415-28 10.1038/nrc2131 1474-175X Nature reviews. Cancer 17508028 http://hdl.handle.net/20.500.12105/17456 Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?