2026-04-27T07:53:35Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/173852024-11-29T09:19:26Zcom_20.500.12105_2052com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19613col_20.500.12105_16973col_20.500.12105_16984
Repisalud
author
Catalá-López, Ferrán
author
Ridao, Manuel
author
Tejedor Romero, Laura
author
Caulley, Lisa
author
Hutton, Brian
author
Husereau, Don
author
Alonso-Arroyo, Adolfo
author
Bernal-Delgado, Enrique
author
Drummond, Michael F
author
Moher, David
funder
Instituto de Salud Carlos III
funder
Centro de Investigación Biomédica en Red - CIBERSAM (Salud Mental)
funder
University of Ottawa (Canadá)
2024-01-31T09:01:42Z
2024-01-31T09:01:42Z
2024-01
J Clin Epidemiol. 2024:165:111208.
http://hdl.handle.net/20.500.12105/17385
37939742
10.1016/j.jclinepi.2023.10.024
1878-5921
Journal of clinical epidemiology
Objectives: To investigate the extent to which articles of economic evaluations of healthcare interventions indexed in MEDLINE incorporate research practices that promote transparency, openness, and reproducibility. Study design and setting: We evaluated a random sample of health economic evaluations indexed in MEDLINE during 2019. We included articles written in English reporting an incremental cost-effectiveness ratio in terms of costs per life years gained, quality-adjusted life years, and/or disability-adjusted life years. Reproducible research practices, openness, and transparency in each article were extracted in duplicate. We explored whether reproducible research practices were associated with self-report use of a guideline. Results: We included 200 studies published in 147 journals. Almost half were published as open access articles (n = 93; 47%). Most studies (n = 150; 75%) were model-based economic evaluations. In 109 (55%) studies, authors self-reported use a guideline (e.g., for study conduct or reporting). Few studies (n = 31; 16%) reported working from a protocol. In 112 (56%) studies, authors reported the data needed to recreate the incremental cost-effectiveness ratio for the base case analysis. This percentage was higher in studies using a guideline than studies not using a guideline (72/109 [66%] with guideline vs. 40/91 [44%] without guideline; risk ratio 1.50, 95% confidence interval 1.15-1.97). Only 10 (5%) studies mentioned access to raw data and analytic code for reanalyses. Conclusion: Transparency, openness, and reproducible research practices are frequently underused in health economic evaluations. This study provides baseline data to compare future progress in the field.
eng
Cost-effectiveness analysis
Data sharing
Economic evaluation
Methodology
Quality
Reporting
Reproducibility
Transparency, openness, and reproducible research practices are frequently underused in health economic evaluations
research article
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TransparencyOpennessReproducibleResearchPractices_2024.pdf
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Supplementary_TransparencyOpennessReproducibleResearchPractices_2024.pdf
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TransparencyOpennessReproducibleResearchPractices_2024.pdf.txt
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Supplementary_TransparencyOpennessReproducibleResearchPractices_2024.pdf.txt